病毒性心肌炎患者血清CK-MB、hs-CRP、IL-35及cTnI水平的表达  

Expression of Serum CK-MB,hs-CRP,IL-35 and cTnI Levels in Viral Myocarditis

作　　者：顾熙东 章晓鹰[1] 徐金龙[1] 陈君灏[1] 杨森[1] GU Xi-dong ZHANG Xiao-ying XU Jindong CHEN Jun-hao YANG Sen(Department of Laboratory Mechicine, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China)

机构地区：[1]上海中医药大学附属曙光医院检验科,上海201203

出　　处：《现代生物医学进展》2017年第6期1099-1101,共3页Progress in Modern Biomedicine

摘　　要：目的:研究血清肌酸激酶同工酶(CK-MB)、超敏C-反应蛋白(hs-CRP)、白介素-35(IL-35)和肌钙蛋白(cTnI)对病毒性心肌炎的诊断意义。方法:研究对象为我院2012年1月至2015年1月间接受诊治的病毒性心肌炎病人63例,作为实验组,选取我院同时期健康体检人60例为对照组。对照两组血清CK-MB、hs-CRP、IL-35及cTnI的检测水平。结果:实验组CK-MB、hs-CRP及cTnI阳性率均明显高于对照组差异有统计学意义(P<0.05);实验组的血清CK-MB、hs-CRP、IL-35及cTnI的检测结果:均明显高于对照组差异有统计学意义(P<0.05);cTnI敏感度及特异度均是最高的,hs-CRP特异度高于CK-MB,但敏感度较低。结论:病毒性心肌炎患者血清CK-MB、hs-CRP、IL-35及cTnI可作为诊断的重要指标。Objective：To explore the diagnosis value of serum creatine kinase（CK-MB）,high-sensitivity C-reactive protein（hs-CRP）,interleukin-35（IL-35） and troponin I（cTnI） in viral myocarditis.Methods：The research subjects were 63 cases of patients with viral myocarditis who diagnosed and accepted treatment in our hospital between January 2012 to January 2015,as the experimental group;while 60 cases of healthy people in our hospital as the same period as a control group.Compared the levels of serum CK-MB,hs-CRP,IL-35,and cTnI in two groups.Results：The positive rates of CK-MB,hs-CRP,cTnI in experimental group were significantly higher than control group,the differences were statistically significant（P〈0.05）;The levels of serum CK-MB,hs-CRP,L-35 and cTnI test results were significantly higher than the control group,the differences were statistically significant（P〈0.05）;The sensitivity and specificity of cTnI were highest,and the specificity of hs-CRP was higher than CK-MB,but the sensitivity was lower.Conclusion：Serum hs-CRP,CK-MB,cTnI and IL-35 can be used as an important indicator of the diagnosis of viral myocarditis.

关 键 词：病毒性心肌炎 CK-MB HS-CRP IL-35 CTNI 

分 类 号：R542.21[医药卫生—心血管疾病]