MSCT和CTPI在外伤性弥漫脑肿胀中的应用效果对比  

Application effect comparison of MSCT and CTPI in evaluation of traumatic diffuse brain swelling

作　　者：张可[1] 柳少光[1] 张建华 魏晓东[1] 张冬志[1] 

机构地区：[1]甘肃省人民医院急诊中心,甘肃兰州730000 [2]兰州市肺科医院,甘肃兰州730046

出　　处：《中国当代医药》2017年第7期145-146,149,共3页China Modern Medicine

基　　金：甘肃省自然科学基金项目(145RJZA066)

摘　　要：目的比较颅脑多排螺旋CT(MSCT)和CT脑灌注成像(CTPI)在外伤性弥漫脑肿胀(DBS)中的应用效果。方法选取2015年1月~2016年10月收治的100例DBS患者作为研究对象,使用GE light speed 64排螺旋CT机扫描,在伤后2~6 h内行常规MSCT检查和CTPI检查,72 h内再次复查CTPI。比较MSCT与CTPI的DBS检出率,分析脑血流量(CBF)、脑血容量(CBV)、平均通过时间(MTT)和超清彩色图像与DBS预后的关系。结果 MSCT对DBS的检出率为88.0%,低于CTPI的96.0%(P<0.01)。治疗后,患者的CBF、CBV呈升高趋势,初次检查与复查CBF、CBV、MTT值比较,差异有统计学意义(P<0.01)。结论 MSCT和CTPI在DBS中具有较好的应用效果,但CTPI能够有效评估患者的预后情况,通过超前彩色图像可直观观察和评价患者的病情变化,值得在临床中推广应用。Objective To compare the application effect of brain multi-slice spiral CT （MSCT） and CT perfusion imag- ing （CTPI） in evaluation of traumatic diffuse brain swelling （DBS）.Methods Altogether 100 cases of patients with DBS from January 2015 to October 2016 were selected as study object.All the patients were scanned by using GE light speed 64-slice spiral CT machine and underwent conventional MSCT and CTPI examinations at 2 to 6 hours after in- jury and CTPI re-examinations within 72 hours.The detection rate of DBS by using MSCT and CTPI were compared, cerebral blood flow （CBF）,cerebral blood volume （CBV）,mean transit time （MTT） and the relationship between ultra clear color images and prognosis of DBS were analyzed.Results The detection rate of DBS by using MSCT was 88.0%, significantly lower than that of CTPI （96.0%）（P〈0.01）;after treatment,CBF and CBV was increased,while MTT was de- creased,the difference of CBF,CBV and MTF between initial examination and reexamination was statistically significant （P〈0.01）.Conclusion MSCT and CTPI have good application effect in evaluation of DBS,but CTPI can effectively assess the prognosis of patients.By using the color image,disease change can be directly evaluated and observed,which is wor- thy of clinical application.

关 键 词：多排螺旋CT CT脑灌注成像 外伤性弥漫脑肿胀 

分 类 号：R816.1[医药卫生—放射医学]