肾实质性高血压中医证候及用药规律文献研究  

Literature Research on Chinese Medicine Syndrome and Related Medicine Law of Renal Parenchymal Hypertension

作　　者：武曦蔼[1] 严美花[1] 张志远[1] 王思轩[1] 段军[1] 

机构地区：[1]中日友好医院,北京市朝阳区樱花东路2号100029

出　　处：《中医杂志》2017年第7期597-600,共4页Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(81302942)

摘　　要：目的通过文献分析肾实质性高血压中医证候及用药规律。方法检索中国生物医学文献数据库、中国期刊全文数据库、万方医学期刊数据库1996年1月至2016年3月中药治疗肾实质性高血压的临床研究文献,提取纳入文献中证型、治法及用药信息,并对各指标进行频数统计分析。结果最终纳入文献26篇,涉及患者1680例。纳入文献中23项研究(88.5%)认为肾实质性高血压中医证候特点为本虚标实证,其中本虚证出现频次前3位为肝肾阴虚(15次)、脾肾阳虚(7次)、阴阳俱虚(5次),标实证出现频次前3位为肝阳上亢(12次)、瘀血内阻(11次)、水湿内停(4次)。26篇纳入文献所用中药共计109味,其类别以滋补肝肾、平肝熄风、活血化瘀、健脾利湿药为主;使用中成药的研究有6项,包括黄芪注射液3项、全杜仲胶囊、舒血宁注射液、黄葵胶囊各1项;使用中药复方的研究有20项,包括单一固定复方9项、基本方随证加减6项、分证论治5项。结论肾实质性高血压为本虚标实之证,其本虚以肝肾阴亏为主,标实以虚阳上亢、瘀血水停为主;中药治疗多以滋补肝肾、平肝潜阳、活血化瘀为法。Objective To analyze Chinese medicine syndrome and related medicine law of renal parenchymal hypertension by literature research. Methods Retrieved clinical study on Chinese herbs treating renal parenchymal hypertension from January 1996 to March 2016 in Chinese Biomedical Literature Database,Chinese Journal Full-text Database,Wanfang Medical Journal Database,extracted the Chinese medicine syndrome types,treatment methods and medication information,and then provided frequency statistics analysis for each measurement. Results Finally26 articles involving 1680 patients were included. In 23 studies（88. 5%） suggested that Chinese medicine syndrome feature was defiency in origin and excess in superficiality. As for defiency in origin,the 3 most frequent syndromes were Yin deficiency in liver and kidney（15）,Yang deficiency in spleen and kidney（7）,as well as Yin-Yang deficiency（5）. As for excess in superficiality,the 3 most frequent syndromes were liver-Yang hyperactivity（12）,blood-stasis obstructing in the interior（11）,as well as water and dampness retention（4）. Totally there were 109 Chinese herbs being used,and the categories of herbs were mainly nourishing liver and kidney,calming liver wind,promoting blood circulation to remove blood stasis,as well as nourishing spleen and eliminating dampness. There were6 studies using Chinese patent medicine,including Huangqi Injection（黄芪注射液,3 studies）,Quanduzhong Capsule（全杜仲胶囊,1 study）,Shuxuening Injection（舒血宁注射液,1 study） and Huangkui Capsule（黄葵胶囊,1 study）.There were 20 studies using Chinese herbal compound,including single fixed compound（9 studies）,basic compound modified with different syndromes（6 studies）,and treatment according to syndromes（5 studies）. Conclusion Renal parenchymal hypertension belongs to defiency in origin and excess in superficiality syndrome. As for defiency in origin,the most frequent syndrome was Yin deficiency in liver and kidney. As for excess in superficial

关 键 词：肾实质性高血压 中医证候 肝肾阴亏 虚阳上亢 瘀血水停 

分 类 号：R259[医药卫生—中西医结合]