联合3种快速试剂用于HIV感染诊断的可行性探讨  

Feasibility study on combination of three kinds of rapid reagents used for HIV infection diagnosis

作　　者：陈会超[1] 冯瑞琳[2] 杨朝军[1] 董莉娟[1] 胡斌[2] 廖斌[2] 戴洁[1] 陈敏[1] 金晓媚[1] 马艳玲[1] 贾曼红[1] 

机构地区：[1]云南省疾病预防控制中心性病艾滋病防制所,昆明650022 [2]昆明市疾病预防控制中心,昆明650000

出　　处：《中国艾滋病性病》2017年第3期251-253,共3页Chinese Journal of Aids & STD

摘　　要：目的探讨联合3种快速试剂用于HIV感染诊断的可行性。方法对所有筛查阳性的样本同时使用6种快速检测试剂和蛋白印迹法(WB)检测,WB不确定者进行随访和核酸检测。以WB阳性,或WB不确定、核酸阳性为HIV感染的判断标准,比较分析3种快速试剂组合与HIV感染诊断结果的一致性。结果在20种组合中,16种组合与HIV感染状况的一致性为100%,4种组合与HIV感染诊断结果一致性为99.81%。结论联合3种快速试剂可用于HIV感染的诊断。Objective To explore the feasibility on the combination of three kinds of rapid reagents used for HIV infection diagnosis. Methods Six kinds of rapid reagents and western blot （WB） were simultaneously applied to de- tect all screened positive samples, HIV antibody indeterminate samples were subjected to follow-up and nucleic acid test for the diagnosis of HIV infection. The standard of HIV infection was WB positive, or WB indeterminate, nu- cleic acid positive. The results of the combination of three kinds of rapid reagent were compared with HIV infection diagnosis. Results Of all the combinations, the consistency rate of 16 combinations and HIV infection diagnosis re- sults was 100%, and the other 4 combinations and HIV infection diagnosis results was 99.81%. Conclusion The combination of three kinds of rapid reagents can be used for the diagnosis of HIV infection.

关 键 词：艾滋病病毒 快速试剂 蛋白印迹法 诊断 可行性探索 

分 类 号：R512.91[医药卫生—内科学]