组织工程皮肤创面修复动物模型的研究进展  

Research progress on wound repair with tissue engineered skin in animal models

作　　者：何秀叶 宋慧锋[1] 郭希民[2] 

机构地区：[1]解放军总医院第一附属医院烧伤整形科、全军烧伤研究所,北京100048 [2]军事医学科学院基础医学研究所,北京100850

出　　处：《解放军医学杂志》2017年第3期239-242,共4页Medical Journal of Chinese People's Liberation Army

基　　金：国家自然科学基金(81171821,31170926,81170523)~~

摘　　要：组织工程皮肤在临床应用中发挥着重要作用,科技的快速发展更推进了组织工程皮肤的研究。选择合适的用于创面修复的动物模型是客观评价组织工程皮肤的前提。本文按照一般创面修复动物实验流程,从实验动物的选择、创面模型的制作、组织工程皮肤相关的细胞及生物材料、创面愈合评价指标等几个方面重点介绍创面修复动物模型的研究进展,为相关科研工作提供参考与借鉴。Tissue-engineered skin plays an important role in clinical applications, and even the rapid development of science and technology promotes the research about it. Choosing an appropriate animal model for wound repair is the prerequisite for the objective evaluation of the object of study. In this paper, the research progress of animal models of wound repair was introduced from several aspects, such as selection of experimental animals, making of wound models, skin-related cells and materials, wound healing evaluation indexes, etc., hoping to provide reference for later research work.

关 键 词：创面修复 模型 动物 组织工程 生物相容性材料 

分 类 号：R622.1[医药卫生—整形外科]