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作 者:许洁如[1] 陈超[1] 沈宁佳[1] 张永杰[1]
机构地区:[1]第二军医大学东方肝胆外科医院胆道二科,上海200438
出 处:《医学综述》2017年第7期1334-1337,共4页Medical Recapitulate
摘 要:原发性胰腺癌临床症状出现较晚,诊断与治疗难度极大,早期发现并进行规范化综合治疗是改善预后的关键因素。少见病理类型的胰腺癌发病率呈逐年上升趋势,胰腺腺鳞癌和胰腺鳞癌两种亚型尤为明显,且较胰腺腺癌恶性程度高、预后差,其诊疗特殊性已引起关注。胰腺转移癌与原发性胰腺癌鉴别困难,极易造成误诊。原发肿瘤的生物学特性及综合治疗的效果是导致患者生存时间及生存质量差异的原因。The clinical signs and symptoms of primary pancreatic carcinoma appear at a later disease stage ,which leadsto diagnosis and treatment being beset with difficulties. Early detection is a key factor to improve the prognosis and thestandardized comprehensive treatment. Although primary pancreatic adenosquamous carcinoma and squamous cell carcinomaare rare neoplasms,incidence rates for these two subtypes are increasing. Compared to adenocarcinoma, they are character-ized by poorly differentiated histology and worse survival which has caused raising concern. Pancreatic metastases and pri-mary pancreatic carcinoma are very difficult to be identified, so it is very easy to cause misdiagnosis. The biological charac-teristics of the primary tumor and the effect of comprehensive treatment are the reasons for the differences in survival timeand life quality.
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