中药壮骨片治疗原发性骨质疏松症的临床研究及疗效评价  

Research and Therapeutic Evaluation of Zhuanggu Tablet in Treatment of Primary Osteoporosis

作　　者：刘旸[1] 宋松[1] 孙威[1] 

机构地区：[1]沈阳市骨科医院,辽宁沈阳110044

出　　处：《中华中医药学刊》2017年第4期968-970,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：辽宁省科学技术基金项目(2014020186)

摘　　要：目的:观察壮骨片对原发性骨质疏松症疗效的判断。方法:使用随机平行对照方法,将200例患者按就诊序号随机分为两组,即对照组和治疗组各100例。对照组单纯补钙,给予钙尔奇D片1片/d口服;治疗组除予钙片外加用壮骨片4片日2次口服,20 d为1个疗程,两组均用药9个疗程。治疗结束半年内,每一个季度分别对两组病例进行骨密度测定和生化指标测定。结果:壮骨片治疗组显效65例,有效26例,无效9例,恶化无,总有效率91%。补钙对照组显效45例,有效37例,无效18例,恶化无,总有效率82%。治疗组临床症状改善情况明显优于对照组(P<0.05),两组骨密度虽均有增加(P<0.05),但是增加的骨密度值治疗组依然高于对照组(P<0.05)。结论:壮骨片治疗老年性骨质疏松症效果显著,值得推广。Objective： To observe the curative effect of Zhuanggu Tablet on senile osteoporosis. Methods： By the random parallel control method,200 patients were randomly divided into two groups： the control group and the treatment group,100 cases in each. Control group used Caltrate Tablets 1 tablet,once a day. The treatment group were treated with Zhuanggu Tablet on the basis of the above treatment,twice a day. And 2 0 days was a course of treatment. Two groups were treated for 6 months. Results： In the treatment group,65 cases were markedly effective,26 cases effective,9 cases ineffective,0 case worse. The total effective rate was 91%. In the control group,45 cases were markedly effective,37 cases effective,18 cases ineffective,0 case worse. The total effective rate was 82%. The treatment group＇s curative effect was better than that of control group（ P〈0. 05）. Bone mineral densities in the two groups were improved（ P〈0. 05）. The treatment group＇s ascension was better than that of control group（ P〈0. 05）. Conclusion： Zhuanggu Tablet in the treatment of primary osteoporosis has a good effect,worthy of promotion.

关 键 词：老年性 骨质疏松 壮骨片 骨密度 

分 类 号：R259[医药卫生—中西医结合]