楤木茎中1个新三萜皂苷类化合物  

A new saponin from stem of Aralia chinensis

作　　者：章文[1] 马国需[2] 朱乃亮[2] 李宇璐 周兴杨 吴桐宇[4] 王云卿[2] 许旭东[2] 余世春[5] 刘守金[1] ZHANG Wen MA Guo-xu ZHU Nai-liang LI Yu-lu ZHOU Xing-yang WU Tong-yu WANG Yun-qing XU Xu-dong YU Shi-chun LIU Shou-jin(College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China Chinese Academy of Medical Sciences, Peking Union Medical College, Institute of Medicinal Plant Development, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100193, China College of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530001, China Center of Research and Development on Life Sciences and Environment Sciences, Harbin University of Commerce, Harbin 150076, China Aetna Pharmaceutical Biotechnology Limited Liability Company, Hefei 230031, China)

机构地区：[1]安徽中医药大学药学院,安徽合肥230012 [2]中国医学科学院北京协和医学院药用植物研究所,中草药物质基础与资源利用教育部重点实验室,北京100193 [3]广西中医药大学,广西南宁530001 [4]哈尔滨商业大学生命科学与环境科学研究中心,黑龙江哈尔滨150076 [5]安徽省安泰医药生物技术有限责任公司,安徽合肥230031

出　　处：《中草药》2017年第4期635-638,共4页Chinese Traditional and Herbal Drugs

基　　金："重大新药创制"科技重大专项"十二五"计划--综合性新药研究开发技术大平台(2012ZX09301-003)

摘　　要：目的研究楤木Aralia chinensis茎的化学成分。方法采用ODS柱色谱技术对楤木茎的75%乙醇提取物进行分离纯化,采用各种波谱技术进行结构鉴定。结果从楤木茎75%乙醇提取物中分离得到了1个新三萜皂苷化合物,鉴定为3-O-{[β-D-glucopyranosyl-(1→2)]-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl}-oleanolic acid 28-O-β-D-glucopyranosyl ester(1)。结论化合物1为新的三萜皂苷类化合物,命名为楤木茎苷A。Objective To study the chemical constituents from the stem of Aralia chinensis. Methods The constituents were isolated and purified by ODS chromatography repeatedly, and the structure was identified by spectral analysis. Results A new saponin was isolated from the stem of A. chinensis. And its structure was identified as 3-O-{[β-D-glucopyranosyl-（1→2）]-[β-D-glucopyranosyl-（1→6）-β-D-glucopyranosyl-（1→3）]-β-D-glucopyranosyl}-oleanolic acid 28-O-β-D-glucopyranosyl ester （1）. Conclusion Compound 1 is a new saponin named as congmujingnoside A.

关 键 词：楤木属 楤木 三萜皂苷 楤木茎苷A 化学成分 

分 类 号：R284.1[医药卫生—中药学]