基于临床文献探讨冠心病气阴两虚证动物模型的评价标准  

Evaluation criteria of animal model of coronary heart disease with qi and yin deficiency syndrome based on clinical literature

作　　者：殷佳[1] 宋彦奇 潘晔[1] 高杉[1] 高树明[1] 杨凯伦[1] 艾乐[2] 杨瑾[2] 李琳[1] 于春泉[1] YIN Jia SONG Yan-qi PAN Ye GAO Shan GAO Shu-ming YANG Kai-lun AI Le YANG Jin LI Lin YU Chun-quan(Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China Lerentang Pharmaceutical Factory, Tianjin Zhongxin Pharmaceutical Group Co., Ltd., Tianjin 300112, China)

机构地区：[1]天津中医药大学,天津300193 [2]天津中新药业集团股份有限公司乐仁堂制药厂,天津300112

出　　处：《中草药》2017年第4期798-802,共5页Chinese Traditional and Herbal Drugs

基　　金：国家重点基础研究发展计划("973"计划)项目(2014CB542902)

摘　　要：冠心病是威胁人类健康的高发病,属于中医胸痹、心悸等病范畴,现今冠心病中医证型的动物模型研究逐渐成为中医药研究的热点。通过对冠心病中医证候的相关文献进行全面检索和分析,发现气阴两虚证是冠心病的主要中医证型。将冠心病气阴两虚证作为研究对象,通过严格的纳入标准、排除标准和系统检索,搜集与冠心病气阴两虚证临床试验相关的所有文献,分析其临床评价指标,用以探索冠心病气阴两虚证动物模型的评价指标,旨在建立冠心病气阴两虚证动物模型的评价标准。Coronary heart disease （CHD） is a disease with high incidence which is threat to human health. CHD belongs to the chest pain, palpitations, etc in traditional Chinese medicine （TCM）. Nowadays the research on TCM syndrome type of coronary artery disease animal model gradually becomes hot topics in the study of traditional Chinese medicine. Through the comprehensive retrieval and analysis of the related literatures of TCM syndromes of CHD, it is found that qi and yin deficiency syndrome is the main type of syndrome of CHD. This article takes CHD qi and yin deficiency syndrome as the research object, through the strict inclusion and exclusion criteria and retrieval system, all the literatures related to clinical trials of CHD qi and yin deficiency syndrome were collected. Through the analysis on literatures of clinical evaluation, the evaluation indexes of CHD qi and yin deficiency syndrome animal model are explored, and aims to build evaluation standard for CHD qi andyin deficiency syndrome animal model.

关 键 词：冠心病 气阴两虚证 临床试验 动物模型 评价指标 

分 类 号：R285[医药卫生—中药学]