延胡索抗阿片类药物成瘾的研究进展  

Research progress on Corydalis yanhusuo in opioid addiction

作　　者：余守洋[1] 杨培润[1] 罗素元[1] 

机构地区：[1]遵义医学院细胞生物学教研室,贵州遵义563000

出　　处：《中草药》2017年第6期1250-1254,共5页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(30860373);遵义医学院博士启动基金(F586)

摘　　要：延胡索及有效成分四氢巴马汀镇痛疗效确切,并具有扩张血管、保护心肌、抗菌、抗炎等功效,临床用于多种疾病的治疗。延胡索为中药戒毒常用药,现就延胡索的化学成分、相关药理作用以及抗阿片类药物成瘾的基础研究进展进行综述,为延胡索的现代化研究和综合利用提供科学依据。Corydalis yanhusuo and its active ingredients dl-THP have clear efficacy of analgesia, as well as the effect on vasodilatation, cardiac muscle protection, antibiosis, and anti-inflammation, thus they are used for the treatment of various disease. In recent years, C. yanhusuo is widely used for the treatment of drug addiction. In this paper, the research progress in the chemical constituents and pharmacologic actions of C. yanhusuo are reviewed, which provide the scientific basis for its modernization research and comprehensive utilization.

关 键 词：延胡索 四氢巴马汀 阿片类成瘾 躯体依赖 精神依赖 

分 类 号：R285[医药卫生—中药学]