声带曲霉病一例报告及文献复习  

Vocal cord aspergillosis: a case report and literature review

作　　者：曹武[1] 关兵 Saroj Kafle 戴炳译 

机构地区：[1]中南大学湘雅二医院耳鼻咽喉科,湖南省长沙市410000 [2]江苏省扬州大学临床医学院,江苏省苏北人民医院耳鼻咽喉科

出　　处：《中国中西医结合耳鼻咽喉科杂志》2017年第1期53-56,43,共5页Chinese Journal of Otorhinolaryngology in Integrative Medicine

摘　　要：目的探讨声带真菌感染的临床特点、诊断和疗效。方法报告1例50岁女性患者因电子喉镜检查提示声带白斑于2015年5月16日就诊我院的临床资料及诊治经过。通过应用CNKI、VIP、万方、Pub Med等中英文数据库检索1995~2015年声带真菌感染的相关文献。共获得来自23篇文献共计33例声带真菌感染患者的资料。结果该例患者行手术治疗,术后病理提示声带真菌感染。将该例患者与既往报道的33例声带真菌感染患者合并分析,结果显示:男12例,女22例,平均年龄42.7岁,临床表现以声嘶为主,其中手术治疗8例,均予抗真菌治疗。结论声带真菌病罕见,临床表现不典型,早期易误诊,诊断需依靠病理检查,全身或局部抗真菌治疗是其主要治疗方法,预后良好。Objective To explore the clinical features, diagnosis and treatment of the fungal infection of vocal cords. Methods 50 years old female patient who was reported as vocal cord leukoplakia on fibreoptic laryngoscopy （May 16, 2015） was treated in our hospital. Literature was retrieval about vocal cord aspergillosis by CNKI, VIP, Wan Fang and PubMed in English database from 1995-2015. Total 34 cases of vocal cord aspergillosis was obtained from 24 articles. Results The patient was treated with surgery, postoperative pathological findings was vocal cord aspergillosis. Combined analysis of 33 eases of vocal cord aspergillosis was done. The results showed that 12 cases were male, 24 female, mean age was 42.1 years old. The main clinical manifestation was the hoarseness of voice. All patients were treated with antifungal therapy. 9 cases were underwent surgical intervention. Conclusion Vocal cord aspergillosis is rare disease, it＇s clinical manifestation is not typical so easily misdiagnosed in early stage. Diagnosis depends on pathological examination. Systemic or local antifungal therapy is the main treatment method. It has good prognosis.

关 键 词：声带 曲霉菌病 声嘶 文献复习 

分 类 号：R767.4[医药卫生—耳鼻咽喉科]