坦索罗辛在输尿管下段小结石中治疗效果观察  

Observation on effect of tamsulosin in treatment of lower ureteral calculi

作　　者：莫志锋[1] 黄荏钊[1] 莫俊华[1] 

机构地区：[1]东莞市人民医院普济分院泌尿外科,广东523200

出　　处：《齐齐哈尔医学院学报》2016年第36期4498-4500,共3页Journal of Qiqihar Medical University

摘　　要：目的探讨坦索罗辛在输尿管下段小结石中治疗效果。方法选取2014年5月至2016年1月我院收治的输尿管下段小结石患者102例,随机分为干预组和常规组,常规组采用利尿、抗感染及排石颗粒治疗,干预组在常规组基础上联合坦索罗辛治疗,比较两组患者治疗效果、肾绞痛、使用止痛剂、外科干预及不良反应发生率。结果干预组患者治疗总有效率高于常规组(96.08%vs.82.35%,P<0.05)。干预组患者肾绞痛、使用止痛剂、外科治疗发生率均低于常规组(5.88%vs.25.49%,3.92%vs.25.49%,3.92%vs.15.69%,P<0.05)。两组患者心悸、低血压、眩晕、腹泻等药物不良反应发生率比较无统计学意义(P>0.05)。结论坦索罗辛治疗输尿管下段小结石可降低并发症发生率,提高结石排除率,具有显著临床治疗效果。Objective To investigate the effect of tamsulosin in the treatment of lower ureteral calculi.Methods Selected 102 cases of lower ureteral calculi from May 2014 to January 2016 in our hospital,randomly divided them into intervention group and routine group,adopted the diuretic,anti-infection and the row of stone particles for curing the routine group,and in addition to the routine group,applied tamsulosin for curing the intervention group,compared the two groups of patients in treatment,renal colic,analgesic use,surgical intervention and incidence of adverse reactions.Results Total efficiency of patients in the intervention group was better than that of conventional group（96.08% vs.82.35%,P〈0.05）.Renal colic,analgesic use,the incidence of surgical treatment in the intervention group were lower than conventional group（5.88% vs.25.49%,3.92% vs.25.49%,3.92% vs.15.69%,P〈0.05）.Palpitations,hypotension,dizziness,diarrhea and other adverse drug reactions between two groups of patients were not statistically significant（P〉0.05）.Conclusions Tamsulosin treatment of lower ureteral calculi can reduce complications,the incidence of adverse drug reactions and improve the stone of exclusion,which has a significant clinical effect.

关 键 词：输尿管 下段小结石 坦索罗辛 治疗效果 

分 类 号：R45[医药卫生—治疗学]