化痰降浊逐瘀方治疗2型糖尿病痰浊瘀阻证合并血脂异常30例  

Clinical Effect of Huatan Jiangzhuo Zhuyu Prescription in Treatment of Type 2 Diabetes Patients with Phlegm-blood Stasis Syndrome Complicated by Dyslipidemia:An Analysis of 30 Cases

作　　者：李家丽[1] 方朝晖[2] LI Jia-li FANG Zhao-hui(Graduate School of Anhui University of Chinese Medicine, Anhui Hefei 230038, China The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui Hefei 230031, China)

机构地区：[1]安徽中医药大学研究生院,安徽合肥230038 [2]安徽中医药大学第一附属医院,安徽合肥230031

出　　处：《安徽中医药大学学报》2017年第2期14-17,共4页Journal of Anhui University of Chinese Medicine

基　　金：国家中医药管理局中医药重点学科(20091221);国家中医药管理局国家公共卫生服务项目(20131012)

摘　　要：目的观察化痰降浊逐瘀方治疗2型糖尿病痰浊瘀阻证合并血脂异常的临床疗效。方法将60例2型糖尿病痰浊瘀阻证合并血脂异常患者随机分为观察组和对照组,每组30例。对照组给予二甲双胍和血脂康治疗,观察组在对照组基础上加用化痰降浊逐瘀方,疗程为16周。评价两组患者治疗前后中医证候积分,观察两组患者治疗前后糖化血红蛋白、空腹血糖、餐后2h血糖、血脂变化。结果治疗后,两组患者中医证候积分较治疗前均明显下降(P<0.05);两组患者治疗前后中医证候积分差值比较,差异具有统计学意义(P<0.05);两组患者临床疗效的分布比较,差异具有统计学意义(P<0.05);治疗后,两组患者实验室指标较治疗前均显著改善(P<0.05);两组患者治疗前后各项实验室指标差值比较,差异具有统计学意义(P<0.05)。结论化痰降浊逐瘀方可改善2型糖尿病痰浊瘀阻证合并血脂异常患者的症状,降低其血糖水平,调节血脂。Objective To investigate the clinical effect of Huatan Jiangzhuo Zhuyu prescription in the treatment of type 2 diabetes patients with phlegm-blood stasis syndrome complicated with dyslipidemia. Methods A total of 60 type 2 diabetes patients with phlegm-blood stasis syndrome complicated with dyslipidemia were randomly divided into observation group and control group, with 30 patients in each group. The patients in the control group were given metformin combined with Xuezhikang, and those in the observation group were given Huatan Jiangzhuo Zhuyu prescription in addition to the treatment for the control group. The course of treatment was 16 weeks for both groups. The traditional Chinese medicine （TCM） syndrome score was evaluated before and after treatment, and the changes in glycosylated hemo- globin, fasting blood glucose, 2-hour postprandial plasma glucose, and blood lipids after treatment were observed and compared between the two groups. Results After treatment, both groups had a significant reduction in the TCM symptom score （P〈0.05）, and there were significant differences in the TCM symp- tom score before and after treatment between the two groups （P〈0.05）. There was a significant difference in the distribution of clinical outcomes between the two groups （P〈0.05）. Both groups had significant improvements in laboratory parameters after treatment （P〈0.05）, and there were significant differences in these laboratory parameters before and after treatment between the two groups （P〈0.05）. Conclusion Huatan Jiangzhuo Zhuyu prescription can improve symptoms, reduce blood sugar, and regulate blood lipids in type 2 diabetes patients with phlegm-blood Stasis Syndrome complicated with dyslipidemia.

关 键 词：2型糖尿病 血脂异常 痰浊瘀阻证 化痰降浊逐瘀方 

分 类 号：R587.1[医药卫生—内分泌]