尿道前列腺等离子电切术联合益肾逐瘀汤治疗前列腺增生的疗效及对性激素的影响  

Effect of Transurethral Plasmakinetic Resection of Prostate Combined With Yishen Zhuyu Decoction on Benign Prostatic Hyperplasia And Its Effect on Sex Hormones

作　　者：徐章寿 邰鹏 

机构地区：[1]江苏省泰州市中西医结合医院,泰州225300

出　　处：《世界中医药》2016年第12期2697-2700,2704,共5页World Chinese Medicine

基　　金：2014年泰州市社会发展计划项目(编号:2014019)

摘　　要：目的:探讨经尿道前列腺等离子电切术(PKRP)联合益肾逐瘀汤对前列腺增生(BPH)患者的临床疗效及对患者性激素水平的影响。方法:选取2014年3月至2016年6月本院收治BPH患者116例,随机分为对照组(n=58)及观察组(n=58),2组均PKRP治疗,对照组围手术期进行常规治疗,观察组在对照组的基础上加用益肾逐瘀汤治疗。统计2组手术情况及各证型临床疗效;记录并比较2组术前、术后8周临床指标及性激素水平;统计2组术后并发症发生情况。结果:2组术中冲洗液中血红蛋白含量、膀胱冲洗时间及尿管滞留时间差异均无统计学意义(P>0.05);对照组血瘀下焦证、膀胱湿热证、肾阴亏虚证、肾阳不足证及肺热气闭证患者的临床总有效率分别为73.91%、40.00%、46.15%、42.86%及40.00%,分别较观察组的95.45%、83.33%、90.00%、100%及100.00%显著降低(P<0.05);与术前比较,术后8周2组PVR、IPSS评分、QOL评分及观察组E2、LH、FSH激素水平均明显降低,且观察组显著低于对照组(P<0.05或P<0.01);而2组MFR及观察组T、PRL激素水平均明显升高,且观察组显著高于对照组(P<0.01);观察组组并发症发生率为10.34%,显著低于对照组的25.86%(P<0.05)。结论:PKRP联合益肾逐瘀汤可显著改善BPH患者的临床症状,调节患者性激素水平,提高临床疗效并明显减少患者术后并发症的发生,疗效显著优于PKRP术后常规治疗。Objective：To investigate the clinical efficacy of transurethral plasmakinetic resection of prostate（PKRP）combined with Yishen Zhuyu Decoction in the treatment of benign prostatic hyperplasia（BPH）and its influence on sex hormone levels.Methods：A total of 116 cases of March 2014-2016 year in June the hospital treated BPH patients were randomly divided into control group（n=58）and observation group（n =58）,2 groups were treated with PKRP,the control group during the perioperative period of routine treatment,the observation group in the control group and Yishen Zhuyu Decoction treatment.Statistics of 2 groups of surgical conditions and the clinical efficacy of each card type,recorded and compared the preoperative and postoperative 8 weeks clinical index and sex hormone levels in the 2 groups,statistical analysis of postoperative complications of the 2 groups.Results：the liquid content of hemoglobin,bladder washing time and catheter retention time had no significant difference between the 2 groups in flushing（P 〉0.05）;control group,blood stasis syndrome,bladder coke under the damp heat syndrome,kidney yin deficiency,kidney yang deficiency syndrome and lung heat syndrome in patients with closed the total effective rate was 73.91%,40%,respectively 46.15%, 42.86% and 40%,respectively,compared with the observation group 95.45%,83.33%,90%,100% and 100% was significantly decreased（P 〈0.05）;compared with the preoperative,postoperative 8 weeks,2 groups of PVR,IPSS score,QOL score and E2 in the observation group,LH and FSH levels were significantly decreased,and the observation group was significantly lower than that of control group（P 〈0.05 or P 〈0.01）;and the 2 group of MFR and T in the observation group,PRL levels were significantly increased,and the observation group was significantly higher than control group（P 〈0.01 ）;the complication rate of observation group（10.34%）was significantly lower than control group （25.86%）（P 〈0.05 ）.Conclusion：PKRP combined with Yi

关 键 词：前列腺增生 经尿道前列腺等离子电切术 益肾逐瘀汤 性激素 疗效 

分 类 号：R277.5[医药卫生—中医学]