Keggin型磷钨钒杂多酸季铵盐的合成、表征及抑菌效果的研究  

Synthesis,Characterization and Antibacterial Activities of Quaternary Ammonium Salts of Tungstovanadophosphoric Heteropolyacid with Keggin Structure

作　　者：白丽明[1] 吕振兴[2] 张伟东[2] 宋天舒[1] 

机构地区：[1]齐齐哈尔大学化学与化学工程学院,黑龙江齐齐哈尔161006 [2]齐齐哈尔大学材料科学与工程学院,黑龙江齐齐哈尔161006

出　　处：《化学试剂》2017年第4期361-364,共4页Chemical Reagents

基　　金：黑龙江省自然科学基金资助项目(B201314);黑龙江省教育厅资助项目(12521595)

摘　　要：以不同钒原子数取代Keggin型磷钨杂多酸并与十六烷基三甲基溴化铵反应合成了3种杂多酸季铵盐。通过红外光谱(IR)、X-射线衍射(XRD)、紫外(UV)等表征手段确定了杂多酸以及杂多酸季铵盐的结构。结果表明,在红外光谱中,引入钒原子后阴离子负电荷增加,导致相应的特征峰出现红移现象;从X-射线衍射谱图中确定了杂多酸季铵盐的二级结构,最后通过热重分析(TG)得出杂多酸季铵盐所含结晶水的数目。通过杯碟法测试了目标产物对大肠杆菌、金黄色葡萄球菌、枯草芽孢杆菌、蜡样芽孢杆菌的抑菌性能,结果表明杂多酸季铵盐对枯草芽孢杆菌的抑菌能力最好,并且钒原子所占比例越高,抑菌效果越好。Three kinds of quaternary ammonium salts were synthesized with tungstophosphoric acid with Keggin structure replaced by the different number of vanadium atoms,and reacted with hexadecyltrimethyl ammonium bromide.The heteropolyacids and the quaternary ammonium salts were characterized by IR,XRD and UV.The results show that red shift of the corresponding characteristic peak,due to the increase of anion negative charge after the introduction of vanadium atoms,is observed in the IR spectrum,the secondary structure of the quaternary ammonium saltsis confirmed based on X-ray diffraction spectra,and the number of crystal water in the quaternary ammonium salts is measured by TG.Antibacterial activities of the target products on E.coli,Staphylococcus aureus,Bacillus subtilis,Bacillus cereus were investigated by Cylinder Plate Method（Oxford Cup）.Antibacterial activity of the quaternary ammonium saltson Bacillus subtilis is the best,and antibacterial effect is better when the proportion of vanadium atoms is higher.

关 键 词：磷钨钒杂多酸季铵盐 合成 表征 杂多酸活性 

分 类 号：O614.51[理学—无机化学] O614.81[理学—化学]