儿童慢性假性肠梗阻研究进展  

Study progress of chronic intestinal pseudo - obstruction in children

作　　者：赵茜茜[1] 李中跃[1] 

机构地区：[1]重庆医科大学附属儿童医院消化科,400014

出　　处：《中华实用儿科临床杂志》2017年第7期557-560,共4页Chinese Journal of Applied Clinical Pediatrics

摘　　要：慢性假性肠梗阻是由于肠道肌病或神经元病变或间充质病变等引起的肠道运动功能障碍性疾病。临床表现与机械性肠梗阻极为相似，但无机械性梗阻的证据。根据病因可分为原发性和继发性2种。根据胃肠道神经肌肉紊乱特点，分为肌病型、神经病变型及间质病变型，其发生机制各异。有相应的临床表现，结合影像学检查或组织病理学检查等，并除外机械性梗阻，可诊断此病。目前治疗主要为促进肠蠕动，保证患儿的营养供应等。现就近年关于儿童慢性假性肠梗阻的发病机制、临床表现、诊治等方面研究作一综述。Chronic intestinal pseudo -obstruction （CIPO） is an intestinal motility dysfunction caused by intestinal myopathies or neuropathies or mesenehymopathies. The clinical manifestation is almost the same with mechanical intestinal obstruction, but in the absence of any obstruction in the gastrointestinal tract. According to etiology, it can be divided into primary and secondary. While according to gastrointestinal neuromuscular disorders, it can be categorized as myopathy, neuropathy and mesenchymopathy, which have different pathogenesis. The disease with the clinical manifesta- tion,imaging examination or histopathology was diagnosed, but mechanical intestinal obstruction must be excluded. Presently, the therapies of CIPO mainly are stimulating the motility of intestine and ensuring the necessary nutrition of the children. The review is mainly focused on the research progress of the pathogenesis, clinical manifestation, diagnosis ,therapy of pediatric CIPO in recent years.

关 键 词：慢性假性肠梗阻 发病机制 诊断 治疗 儿童 

分 类 号：R725.7[医药卫生—儿科]