极低出生体重儿早期应用无创呼吸支持的效果  

Early application of noninvasive respiratory support benefits very low birth weight infant

作　　者：黎炽旺 张文明[1] 温伟珍[1] 李炎[1] 刘镇滔[1] 温园香[1] 陈宏香[1] 

机构地区：[1]中山大学附属梅州医院,梅州市人民医院新生儿科,514031

出　　处：《实用医学杂志》2017年第5期728-730,共3页The Journal of Practical Medicine

基　　金：梅州市科学技术局2016立项项目(编号:2016B010)

摘　　要：目的:探讨极低出生体重儿(VLBWI)早期应用无创呼吸支持的效果。方法:选择2015年9月至2016年9月在我院产科出生,胎龄28~32周,1 000 g≤出生体重<1 500 g、排除合并先天畸形等的VLBWI,随机分为早期应用无创呼吸支持治疗观察组(33例)和应用气管插管有创呼吸支持治疗对照组(32例)。观察两组患儿气管插管有创呼吸支持率、BPD发病率、肺部感染发生率,总用氧时间、气胸、NEC发生率、抢救成功率等。结果:两组患儿在气胸、NEC发生率、抢救成功率方面比较差异无统计学意义。观察组气管插管有创呼吸支持率、BPD、肺部感染发生率、总用氧时间均低于对照组,差异有统计学意义。结论:在保证患儿抢救成功率的前提下,VLBWI早期应用无创呼吸支持治疗能减少气管插管有创呼吸支持率,减少BPD及肺部感染发生率,提高VLBWI的生存质量。Objective Investigate the effects of early application of noninvasive respiratory support on very low birth weight infant （VLBWI）. Method A total of 65 VLBWI （born during September 2015 to September 2016 with 28-32 weeks gestational age; 1 000 g ≤ birth weight 〈 1 500 g; exclusion of combination with congenital deformity） were randomly divided into the early application of noninvasive respiratory support as observation group （n = 33） and the application of endotracheal intubation with gen respiratory support as control group （n = 32）. Comparison of two groups was carried out by SPSS in terms of incidence of endotracheal intubation, BPD, pulmonary infection, pneumothorax, and necrotizing enterocolitis, together with rescue ratio, total oxygenation time and hospitalization. Results No significant difference was found on incidence of pneumothorax, necrotizing enterocolitis and rescue ratio between two groups. The incidence of endotracheal intubation, BPD, pulmonary infection and total oxygenation time was markly decreased in observation group. Conclusion Early application of noninvasive respiratory support benefits VLBWI via reducing incidence of endotracheal intubation, BPD, pulmonary infection, total oxygenation time.

关 键 词：极低出生体重儿 无创呼吸支持 气管插管 支气管肺发育不良 

分 类 号：R722.6[医药卫生—儿科]