补钙对骨质疏松骨折预防作用的研究进展  

The research progress of preventive efficacy of calcium intake for osteoporotic fracture

作　　者：高春林[1] 姜虹[1] 唐家广[2] 侯树勋[2] 

机构地区：[1]大连医科大学附属大连市友谊医院骨二科,辽宁大连116001 [2]解放军总医院第一附属医院骨科研究所,北京100048

出　　处：《中国当代医药》2017年第9期15-17,共3页China Modern Medicine

基　　金：北京市科委科技计划立项课题(D161100002816003)

摘　　要：补充钙质和维生素D被认为是防治骨质疏松的基本措施,然而其效果却并不理想,研究结论也缺乏一致性。有研究认为,补钙对骨质疏松骨折有预防作用,但也有很多研究得出了否定的结论。而且,对补钙是否应该联合维生素D、补钙的具体途径与具体剂量等问题,还存在许多争议。本文通过收集这方面最新的研究资料,尤其是队列研究、随机对照研究和Meta分析,深入探讨补钙对骨质疏松骨折的预防效果,以期能够帮助人们更合理地制订补钙方案。Calcium and Vitamin D have widely been recommended for older individuals as a basic therapy to prevent osteoporosis and subsequent fractures,but the effect is not very ideal and research conclusion is a lack of consistency. Some studies support the preventive effect of calcium intake for osteoporosis and fractures,but others may not.And it is not yet clear which benefits more,Calcium with or without vitamin D,from dietary or supplementationslwith low or high dose.This review analyzes the high grade evidence,such as cohort studies,randomized controlled studies and Meta analysis from recently published literature,to analyse the efficacy of calcium intake,and present some suggestion for the public to make suitable calcium regime.

关 键 词：骨质疏松症 骨折 钙 维生素D 预防 

分 类 号：R681[医药卫生—骨科学]