经直肠超声引导下前列腺穿刺活检阳性率的临床影响因素分析  

Clinical influence factor analysis of the positive rate of transrectal ultrasound-guided prostate biopsy

作　　者：马文斌[1] 江虹虹[1] 郭顺华[1] 

机构地区：[1]广州市红十字会医院超声诊断科,广东广州510220

出　　处：《中国当代医药》2017年第9期86-88,97,共4页China Modern Medicine

摘　　要：目的探讨经直肠超声引导下前列腺穿刺活检阳性率的临床影响因素。方法抽取2015年1月~2016年12月来我院就医的116例接受经直肠超声引导下前列腺穿刺活检患者作为研究对象,对116例患者的临床资料进行回顾性分析,分析经直肠超声引导下前列腺穿刺活检阳性率的临床影响因素。结果 116例患者中,47例患者为前列腺癌,阳性检出率为40.52%,其中2016年阳性检出率为57.58%,略高于2015年的32.73%;47~54、55~59、60~69、70~79、≥80岁患者的前列腺癌阳性检出率分别为28.57%、33.33%、39.58%、50.00%、50.00%,随着患者年龄的增加,前列腺癌阳性检出率呈现逐渐增加的趋势。PSA浓度4~<10、10~<20、20~<50、50~<100、≥100μg/L患者的前列腺癌阳性检出率分别为33.33%、31.82%、35.71%、50.00%、100.00%,随着患者PSA浓度的增加,前列腺癌阳性检出率呈现逐渐增加的趋势。前列腺体积<20、20~<50、50~<80、80~100 ml患者的前列腺癌检出率分别为31.25%、57.58%、38.00%、23.53%,多组比较差异有统计学意义(P<0.05)。经多因素Logistic回归分析后发现,影响经直肠超声引导下前列腺癌检出率的因素主要包括年龄、PSA浓度及前列腺体积。结论年龄、PSA浓度及前列腺体积均可能影响经直肠超声引导下前列腺穿刺活检的阳性率,因此在进行前列腺穿刺活检时建议排除相关干扰因素。Objective To investigate the clinical influence factors of the positive rate of transrectal uhrasound-guided prostate biopsy.Methods Altogether 116 cases of patients who underwent transrectal ultrasound-guided prostate biopsy in our hospital from January 2015 to December 2016 were involved as the object of this experiment.The clinical data of 116 patients were analyzed retrospectively so as to explore the clinical influence factors of the positive rate of transrectal ultrasound-guided prostate biopsy.Results Of the 116 patients,47 patients were identified as prostate cancer and the positive rate was 40.52%,and the positive rate was 57.58% in 2016,which was slightly higher than that in 2015 （32.73%）. The positive rate of prostate cancers who aged 47-54,55-59,60-69 and 70-79 years old,above 80 years old was 28.57%, 33.33%,39.58%,50.00% and 50.00%;with the increase of age,the positive rate of prostate cancers increased gradually. The positive rate of prostate cancers whose concentration of prostate specific antigen （PSA） ranged from 4-〈10,10-〈20, 20-〈50,50-〈100 to ≥ 100 g/L was 33.33%,31.82%,35.71%,50.00% and 100.O0%,respectively.With the increase of PSA concentration,the positive rate of prostate cancers increased gradually.The detection rate of prostate cancers with the prostate volume ranging from 〈20,20-〈50,50-〈80 to 80-100 ml was 31.25%,57.58%,38.00% and 23.53%,with signifi- cant difference between multiple groups（P〈0.05）.According to the muhivariate Logistics regression analysis,it was found that the influencing factors of the detection rate of transrectal ultrasound-guided prostate cancers mainly included age, PSA concentration and prostate volume.Conclusion Patients＇ age,PSA concentration and prostate volume may affect the positive rate of transreetal ultrasound-guided prostate biopsy,therefore,it is recommended to exclude related interference factors when transrectal prostate biopsy is performed.

关 键 词：经直肠超声 前列腺穿刺活检 阳性 因素 

分 类 号：R445.1[医药卫生—影像医学与核医学]