绝经后女性阵发性房颤经导管射频消融治疗的效果观察  

The efficacy follow-up of radiofrequency catheter ablation for paroxysmal atrial fibrillation in postmenopausal women

作　　者：蔡志雄[1] 黄健强[1] 王莹[1] 薛玉梅[2] 郑海生[1] 马贵洲[1] 陈平[1] 

机构地区：[1]汕头市中心医院心血管内科,广东汕头515000 [2]广东省心血管病研究所,广东省人民医院(广东省医学科学院),广东广州510080

出　　处：《广东医学》2017年第5期700-704,708,共6页Guangdong Medical Journal

基　　金：汕头市科技计划项目(医疗卫生重点项目)(编号:E201200529)

摘　　要：目的观察绝经后女性阵发性房颤行射频消融治疗的效果进行研究。方法阵发性房颤患者186例(绝经后女性66例,绝经前女性30例,与绝经后女性年龄匹配的男性90例),在CARTO 3系统引导下行射频消融,对复发的差异进行生存分析,采用Cox回归分析复发的影响因素。结果单次射频消融治疗后随访中位数23个月,绝经后、绝经前女性和男性的成功率分别为72.92%、84.62%和76.39%,差异无统计学意义(生存曲线分析Log-rank检验P=0.798)。绝经不是复发的影响因素。结论绝经后女性阵发性房颤行射频消融治疗的效果与绝经前女性、同年龄层的男性接近。Objective To investigate the efficacy of radiofrequency catheter ablation （RFCA） on paroxysmal atri- al fibrillation （AF） in postmenopausal women. Methods A total of 186 patients with paroxysmal AF （postmenopausal women group n = 66, premenopausal women group n = 30, men matched with the age group n = 90） underwent RFCA guided by the CARTO 3 system were included. The difference in the outcomes and recurrence of AF among the three groups were assessed. Cox - regression was performed to identify the influencing factors of recurrence. Results After a mean follow - up of 23 months, the success rates of RFCA in postmenopausal women group, premenopausal women group and men group were 72. 92% , 84. 62% and 76. 39% , respectively, with no significant differences among them （ Log - rank test P = 0.798 ）. Menopause was not an influencing factor of recurrence. Conclusion The efficacy of RFCA in post- menopausal women with paroxysmal AF is similar with premenopausal women and men at the similar age.

关 键 词：绝经后女性 阵发性房颤 经导管射频消融 

分 类 号：R541.7[医药卫生—心血管疾病]