IMA、HS-CTNT、CK-MB在ACS危险分层中的研究  

Research on IMA,HS-CTNT and CK-MB in ACS risk stratification

作　　者：葛庆辉 杨丽[2] 彭辉[2] 谢昆[2] 乔荔[2] 郭宇璇 项欣[2] 沙代提古力.米吉提 徐菲莉[2] 

机构地区：[1]新疆医科大学中医学院,乌鲁木齐830000 [2]新疆医科大学附属中医院,乌鲁木齐830000

出　　处：《检验医学与临床》2017年第7期909-910,914,共3页Laboratory Medicine and Clinic

基　　金：国家高技术研究发展计划(2011AA02A111)

摘　　要：目的研究缺血修饰清蛋白(IMA)、超敏肌钙蛋白T(HS-CTNT)、肌酸激酶同工酶(CK-MB)血清水平在急性冠状动脉综合征(ACS)危险分层中的意义。方法测定190例对照组与601例ACS患者(其中包括低危组、中危组、高危组)IMA、HS-CTNT、CK-MB的血清水平。结果低危组、中危组、高危组间IMA水平随危险程度的升高而升高,低危组与高危组之间比较差异有统计学意义(P<0.05),中危组与高危组、低危组之间比较差异无统计学意义(P>0.05),低危组、中危组、高危组与对照组之间比较差异有统计学意义(P<0.05);低危组、中危组、高危组及对照组彼此之间HS-CTNT、CK-MB血清水平比较差异有统计学意义(P<0.05),且随着危险程度的增加,HS-CTNT、CK-MB血清水平不断增高。结论 HS-CTNT、CK-MB、IMA在ACS危险分层及诊断中有一定的临床意义。Objective To study the significance of serum levels of ischemic modified albumin（IMA）,high sensitive troponinT（HS-CTNT）and creatine kinase isoenzyme（CK-MB）in the risk stratification of acute coronary syndrome（ACS）.Methods Serum levels of IMA,HS-CTNT and CK-MB were measured in 190 healthy control people and 601 patients with ACS,including low-risk group,medium-risk group and high-risk group.Results The IMA level in the low risk group,medium risk group and high risk group was increased with the risk degree increase,the difference between the low-risk group and medium-risk group had statistical significance（P〈0.05）,while the difference between the medium-risk group with high-risk group and low-risk group had no statistical significance（P〈0.05）,the difference between the low-risk group,medium-risk group and high-risk group with the control group had statistical significance（P〈0.05）;the serum levels of HS-CTNT and CK-MB had statistical difference between the lowrisk group,medium-risk group and high-risk group with the control group（P〈0.05）;moreover with the risk degree increase,the serum levels of HS-CTNT and CK-MB were gradually increased.Conclusion HS-CTNI,CK-MB and IMA have a certain clinical significance in the risk stratification and diagnosis of ACS.

关 键 词：缺血修饰清蛋白 超敏肌钙蛋白T 肌酸激酶同工酶 危险分层 

分 类 号：R542.22[医药卫生—心血管疾病]