星形胶质细胞在脊髓损伤中的研究展望  

The research and prospect on astrocyte in spinal cord injury

作　　者：沈劲松[1] 徐伟杰[1] 武绍远[1] 李艳华[1] 

机构地区：[1]昆明理工大学医学院,昆明650500

出　　处：《生命科学》2017年第2期170-173,共4页Chinese Bulletin of Life Sciences

基　　金：云南省科技厅-昆明医科大学应用基础研究联合专项(2013FZ298)

摘　　要：近年来星形胶质细胞(astrocyte,AS)已经逐渐成为中枢神经系统(CNS)疾病研究中的热点之一。激活星形胶质细胞会产生和释放神经递质、神经营养因子和促炎因子等,对神经元既有保护作用也有毒性作用。现综述星形胶质细胞的形态、功能以及与脊髓损伤(spinal cord injury,SCI)的联系等,为进一步研究星形胶质细胞和脊髓损伤提供依据。In recent years, astrocyte （AS） has gradually become a hot issue of research in central nervous system （CNS） disease. Activated astrocytes produce and release neurotransmitters, neurotrophic factors and proin- flammatory cytokines which have both protective and toxic effects on neurons. This paper summarizes the relationships between the morphology and function of astrocytes and spinal cord injury （SCI）. Therefore, this review provides some basis for the further surveys of astrocyte and spinal cord injury.

关 键 词：星形胶质细胞 脊髓损伤 轴突再生 突触联系 胶质纤维酸性蛋白质 

分 类 号：Q421[生物学—神经生物学] R651.2[生物学—生理学]