半量尿石通对含钙尿石形成患病因素的影响  

The influence of half dose of Niaoshitong pill on the formation of urinary calcium stone

作　　者：王珅 郭昌华[2] 陈志强[1] 杨为民[1] 叶章群[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院泌尿外科,武汉430030 [2]武汉大学人民医院泌尿外科

出　　处：《临床外科杂志》2017年第3期229-231,共3页Journal of Clinical Surgery

摘　　要：目的分析半量尿石通对含钙尿石形成的影响。方法门诊肾结石患者22例,进行自身对照研究,比较服用半量尿石通1个月前后尿p H值、钙、磷、草酸、尿量、尿酸、酸性黏多糖的变化。结果排出结石7例(31.8%),发生肾绞痛1例,口服扶他林后缓解。均无因不能耐受而中断治疗者,服药期间无明显不良反应发生。钙、磷、草酸、p H值、酸性黏多糖及结石形成概率指数服药后明显改变(P<0.05),尿酸和尿量无明显改变(P>0.05)。结论使用半量尿石通并延长用药时间,对于含钙尿石形成的患病因素有影响,可降低结石形成概率指数。Objective To investigate the effect of Niaoshitong pill, a Chinese herbal medicine, on the formation of urinary calcium stone. Methods 22 patients with urinary stone diagnosed were enrolled in this study. Urine pH, calcium, phosphorus, oxalic acid, urine volume, uric acid and acid mucopolysaecharide（AMPS） were observed before and after taking 1 month of half dose of Niaoshitong pill. Results The stones were completely ejected in 7 cases（31.8% ）,renal colic occurred and resolved with Voltaren in 1 case （4.5%）. No one withdrew for the intolerable therapy. Calcium, phosphorus, oxalic acid, pH, AMPS and the probability of stone formation （Psf） had significantly changed after the treatment （ P 〈 0.05 ）, but no significant changes occurred in uric acid or urine volume （ P 〉 0.05 ）. Conclusion It was demonstrated that half dose of Niaoshitong pill with a longer time had a restraining effect on the risk factors of renal calculus, and it could significantly lower the Psf.

关 键 词：尿石通 肾结石 患病因素 结石形成概率指数 

分 类 号：R691.4[医药卫生—泌尿科学]