声脉冲辐射力弹性成像在移植肝术后早期恢复过程中的评估价值  

Evaluation of application value of acoustic radiation force impulse imaging of transplant liver in early recovery after transplantation

作　　者：范俊儿 朱贤胜[2] 王莎莎[2] 周利利[2] 程琦[2] 

机构地区：[1]广州中医药大学,510405 [2]广州军区广州总医院超声影像科

出　　处：《器官移植》2017年第2期161-164,173,共5页Organ Transplantation

基　　金：广东省自筹经费类科技计划项目(粤科规划字[2013]137号)

摘　　要：目的探讨声脉冲辐射力弹性成像(ARFI)技术在移植肝术后早期恢复过程中的评估价值。方法收集19例行原位肝移植的患者作为研究组,12名健康成年人作为对照组。研究组在移植术后第1、2、3、5、7日接受相关床旁常规超声检查及ARFI检测,比较术后各日移植肝弹性的变化。对照组仅接受1次常规超声检查及ARFI检测。比较研究组和对照组的肝脏二维超声、彩色多普勒超声及ARFI结果。结果常规超声显示研究组移植肝1周内恢复良好;ARFI显示移植肝术后第1、2、3、5、7日的剪切波速度(SWV)值均高于健康成年人,差异均有统计学意义(均为P<0.05)。术后第1日的SWV值高于第7日,差异有统计学意义(P<0.05)。结论ARFI技术能够显示移植肝术后早期肝脏硬度与健康人的区别,可反映早期肝脏硬度的变化,具有良好临床应用价值。Objective To evaluate the application value of acoustic radiation force impulse imaging （ARF1） in the early recovery of transplant liver. Methods Nineteen patients undergoing orthotopic liver transplantation were assigned into the study group and 12 healthy adults were recruited in the control group. In the study group, patients received bedside conventional ultrasound and ARFI examination at 1,2,3,5 and 7 d after liver transplantation to observe the change of transplant liver elasticity, and those in the control group underwent once conventional ultrasound and ARFI examination. Two-dimensional liver ultrasound, color Doppler ultrasound and ARFI findings were statistically compared between the study and Control groups. Results Conventional ultrasound demonstrated that the liver graft was properly recovered within 1 week after liver transplantation. ARFI revealed that the shear ware velocity （SWV） at 1,2,3,5 and 7 d after liver transplantation was significantly higher than that in the control group （all P〈0.05）. The SWV at postoperative 1 d was significantly higher than that at postoperative 7 d （P〈0.05）. Conclusions ARFI can distinguish the liver stiffness between patients early after liver transplantation and healthy controls, and reflect the early variation of liver stiffness with good clinical application value.

关 键 词：声脉冲辐射力弹性成像 剪切波速度 移植肝 肝硬度变化 

分 类 号：R617[医药卫生—外科学] R445.1[医药卫生—临床医学]