UA水平与急性STEMI患者院内死亡关系的研究  

Relationship between UA Level and In-hospital Mortality in Patients with Acute STEMI

作　　者：姚计文 王学东[1] 汪钰[1] 

机构地区：[1]北京市和平里医院CCU病房,北京100013

出　　处：《中国医药导刊》2017年第3期229-230,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨血清尿酸(UA)水平与急性ST段抬高型心肌梗死(STEMI)患者院内死亡的关系。方法:71例STEMI患者按UA水平420μmol/L分为两组:A组(UA升高组,>420μmol/L)37例,B组(UA正常组,<420μmol/L)34例,分析两组临床资料特征和实验室检查结果,多因素回归分析血清UA与STEMI患者院内死亡的相关性。结果:与B组相比,A组的HsCRP、BNP、TNI水平及院内死亡率均显著升高(P均<0.05)。多因素分析中,血清UA和TNI是与STEMI患者发生院内死亡的独立相关变量(P<0.05)。结论:UA水平升高与STEMI患者发生院内死亡有关,机制可能是高水平的UA促进了机体氧化应激程度增强。Objective：To study the relationship between serum uric acid（UA） level and in-hospital mortality in patients with acute ST segment elevation myocardial infarction（STEMI）.Methods：71 cases of STEMI patients according to the level of U A 420 mol/L divided into two groups：A group（UA group,420μmol/L） 37 cases,group B（normal UA group,420μmol/L） in 34 cases,analysis of two groups of clinical features and laboratory findings,multivariate regression analysis of serum U A related deaths patients with STEMI in hospital.Results：Compared with B group,the levels of HsCRP,BNP,TNI and in-hospital mortality were significantly higher in A group（P〈0.05）.In multivariate analysis,serum UA and TNI were independent variables associated with in-hospital mortality in patients with STEMI（P〈0.05）.Conclusions：Elevated UA levels are associated with in-hospital mortality in patients with STEMI,and the mechanism may be that elevated levels of UA promote increased oxidative stress.

关 键 词：尿酸 急性ST段抬高型心肌梗死 院内死亡 

分 类 号：R542.22[医药卫生—心血管疾病]