UA患者冠脉狭窄程度与超敏C-反应蛋白、脂蛋白a的关系探讨  

Relationship between the Degree of Coronary Artery Stenosis and the High Sensitivity C-Reactive Protein and Lipoprotein A in Patients with UA

作　　者：刘庚[1] 卢清玉[1] 常宇锋[1] 

机构地区：[1]北京市海淀医院心内科,北京100080

出　　处：《中国医药导刊》2017年第3期239-240,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探究不稳定型心绞痛(UA)患者冠脉狭窄程度与血清超敏C-反应蛋白(hs-CRP)、脂蛋白a(Lp-a)的相关性。方法:选取我院收治的271例UA患者为研究对象,所有患者均接受冠脉造影检查,并检测血清hs-CRP和Lp-a水平,统计分析相关数据。结果:271例UA患者中,0支病变29例(10.70%),1支病变43例(15.87%),2支病变89例(32.84%),3支及以上病变110例(40.59%),不同血管病变患者血清hs-CRP、Lp-a水平比较均有统计学差异(P=0.000<0.05)。随着冠脉狭窄程度的增加血清hs-CRP、Lp-a水平也升高(r=0.817,0.561,P<0.05)。结论:UA的防治及预后评价应充分考虑患者病情并结合患者的hsCRP、Lp-a水平。Objective：To investigate the relationship between the degree of coronary artery stenosis and serum high sensitivity C-reactive protein（hs-CRP） and lipoprotein a（Lp-a） in patients with unstable angina pectoris（UA）.Methods：271 patients with UA in our hospital were selected as the research object,all patients underwent coronary angiography,and serum hs-CRP and Lp-a levels were detected.Results：271 cases of UA patients,0 lesions in 29 cases（10.70%）,1 lesions in 43 cases（15.87%）,2 lesions in 89 cases（32.84%）,3 and above lesions in 110 cases（40.59%）,different vascular lesions in patients with serum hs-CRP,Lp-a levels were statistically significant（P = 0.000 0.05）.The level of serum hs-CRP and Lp-a increased with the degree of coronary artery stenosis（r =0.817,0.561,P 0.05）.Conclusion：Lp-a should be taken into account in the prevention and treatment of UA and the prognosis of patients with hs-CRP and the level of the patients.

关 键 词：不稳定型心绞痛 超敏C反应蛋白 脂蛋白A 

分 类 号：R541.4[医药卫生—心血管疾病]