甲状腺功能仪测定吸碘率的影响因素  

Analysis of influencing factors of detecting radioactive iodine uptake by using thyroid function instrument

作　　者：宋娟娟[1] 李建红[1] 王荣福[1,2] 

机构地区：[1]北京大学国际医院核医学科,北京102206 [2]北京大学第一医院核医学科,北京100034

出　　处：《中国医学装备》2017年第4期24-27,共4页China Medical Equipment

基　　金：国家重大科学仪器设备开发专项(2011YQ03011409)"基于多模态分子影像技术的新型肿瘤新生血管靶向显像剂及治疗药物研究";国家"十二五"支撑项目(2014BAA03B03)"~(99)Tc~m-RRL新型靶向肿瘤新生血管放射性药物的实验研究"

摘　　要：甲状腺摄碘-131(^(131)I)率在确定甲状腺机能亢进碘治疗剂量及判断甲状腺功能方面具有重要价值。利用甲状腺功能仪测量摄碘率值受多种因素影响,其中包括仪器因素、甲状腺测量、标准源及本底测量、含碘药物、食物、抗甲状腺药物以及其他因素,均会在不同程度上影响测量值。在临床中时常会出现摄碘率测量不正规的问题,因此必须重视摄碘率测定规范化操作,对甲状腺功能仪测量进行质量控制,为临床甲状腺机能亢进病症诊断和治疗提供优质可信的摄碘率值。The radioactive iodine uptake（RAIU） has great value in determining the 131I treatment dosage of patients suffered from hyperthyroidism and judging thyroid function. Many factors which could interfere the results of RAIU were as follows： instrumental factors, thyroid radioactivity counts measurement, counts of a calibrated standard in a neck phantom and counts of room background, iodinated drugs and food, anti-thyroid medication, among other causes, have shown to induce varying degrees of errors in RAIU measurements. Irregular measurements which may interfere with radioactive iodine uptake are commonly seen in clinical practice, yet its actual influence has not been reported. Optimization, regularization and quality control of the radioiodine uptake measurement are essentials for clinical routine practice to guarantee appropriate values for clinical hyperthyroidism diagnosis and treatment. All the above factors affecting the measurement of thyroid function instrument for radioactive iodine uptake are analyzed and then put forward the corresponding solutions.

关 键 词：甲状腺功能仪 甲状腺摄碘-131率 质量控制 

分 类 号：R817.8[医药卫生—影像医学与核医学]