虎黄烧伤搽剂治疗Ⅱ度烧伤的临床研究  

Multi-center clinical study of the Huhang Burn Liniment accelerate healing of second degree burn wounds

作　　者：常东方[1] 邱林[2] 张恒术[3] 杨登齐 Chang Dongfang Qiu Lin Zhang Hengshu gang Dengqi(Department of Burns ,Yongchuan Hospital Affiliated to Chongqing Medical University ,Chongqing 402160 ,China Department of Burns, Children＇s Hospital Affiliated to Chongqing Medical University, Chongqing 400014, China Department of Burns, the First Affiliated Hospital of Chongqing Medical University ,Chongqing 400016, China Department of Burns, Seventh People Js Hospital of Chongqing City, Chongqing 400045,China)

机构地区：[1]重庆医科大学附属永川医院烧伤科,402160 [2]重庆医科大学附属儿童医院烧伤科,400014 [3]重庆医科大学附属第一医院烧伤科,400016 [4]重庆市第七人民医院烧伤科,400045

出　　处：《重庆医学》2017年第11期1482-1483,1486,共3页Chongqing medicine

摘　　要：目的探讨虎黄烧伤搽剂治疗Ⅱ度烧伤的临床效果及安全性。方法入选4个研究中心收治的400例Ⅱ度烧伤患者,分为治疗组和对照组,每组200例。治疗组采用外用虎黄烧伤搽剂,对照组采用外用磺胺嘧啶银糊剂,比较两组患者创面愈合情况、用药安全性及治疗效果。结果治疗组烧伤的创面愈合时间明显短于对照组(P<0.05)。治疗前两组创面细菌感染率和视觉模拟评分法(VAS评分)差异无统计学意义(P>0.05);治疗后,治疗组细菌感染率及疼痛减轻程度均明显优于对照组(P<0.05)。治疗组痊治愈率和有效率均较对照组高(P<0.05)。结论虎黄烧伤搽剂对于Ⅱ度烧伤可有效地促进伤口愈合、局部抑制细菌生长,安全可靠。Objective To evaluate the clinical efficacy and safety of the Huhang Burn Liniment in the treatment of Ⅱ degree burn wounds. Methods 400 cases of Ⅱ degree burn patients admitted to the 4 research centers were divided into two groups（n= 200）. The treatment group was treated with external Huhang Burn Liniment and the control group was treated with topical silver sulfadiazine sliver paste. The wound healing, safety and effect of treatment were compared between two groups. Results The wound healing time in treatment group was significantly better than that of control group （P〈0. 05）. Before treatment, there was no significant difference in bacterial infection rate and VAS score between two groups. After t.reatment, the bacterial infection rate and the degree of pain relief in the treatment group were significantly better than those in control group（P〈0.05）. The cure rate and total effective rate in treatment group were 84.0K and 97.5% respectively, while the control group were 72% and 87%, the difference were statistically significant （P〈0.05）. Conclusion The Huhang Burn Liniment can effectively promote wound healing, inhibit the growth of bacteria, it＇s safe and reliable.

关 键 词：虎黄烧伤搽剂 烧伤 多中心 

分 类 号：R269[医药卫生—中西医结合]