肝纤维化的MRI研究进展评述  

Liver fibrosis on magnetic resonance imaging:current status

作　　者：陈天武[1] 陈繁[1] 陈艳丽[1] 吴兰[1] 蒋宇[1] CHEN Tianwu CHEN Fan CHEN Yanli WU Lan JIANG Yu(Sichuan Key Laboratory of Medical Imaging, Department of Radiology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan, Chin)

机构地区：[1]四川省医学影像重点实验室.川北医学院附属医院放射科,四川南充637000

出　　处：《西部医学》2017年第4期450-454,共5页Medical Journal of West China

基　　金：国家自然科学基金(81050033);四川省科技支撑计划项目(2011SZ0237)

摘　　要：肝纤维化是各种慢性肝病共有的病理改变。早期肝纤维化是可逆转的,因此早期诊断肝纤维化有助于及时干预疾病进展及控制肝硬化、肝癌的发生。但临床对于肝纤维化的诊断金标准是穿刺活检,属有创检查,因此需要使用一种无创、可重复、定量检查技术来诊断肝纤维化。磁共振成像(MRI)作为一种无辐射、无损伤、组织分辨率高、可重复性好的检查手段,尤其是近几年MRI软硬件的升级,使它逐渐成为研究的热点,本文就肝纤维化的MRI研究进展作一述评。Liver fibrosis is the common pathological changes of a variety of chronic liver diseases. The early liver fibrosis is reversible, and then early diagnosis of liver fibrosis can be helpful for timely and effectively intervening the pro- gression of fibrosis and the occurrence of liver cirrhosis or liver cancer. However, the golden standard for the diagnosis of liver fibrosis is biopsy. Because of invasive nature of biopsy, a noninvasive and repeatable quantitative examination tech- nology is needed to diagnose liver fibrosis. As a noninvasive method, magnetic resonance imaging is a technology with no radiation, high resolution of tissue and good repeatability of measurement, and the hardware and software have been up- graded. Magnetic resonance imaging of liver fibrosis has become a hot research theme during recent years. In this paper, we will review the current status of magnetic resonance imaging in liver fibrosis.

关 键 词：肝纤维化 肝硬化 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学]