有创及无创序贯性机械通气治疗慢性阻塞性肺疾病所致严重呼吸衰竭疗效观察  

Clinical observation of invasive and non-invasive sequential mechanical ventilation in treatment of severe respiratory failure caused by chronic obstructive pulmonary disease

作　　者：邓鸣林[1] DENG Minglin(The First People＇s Hospital of Liangshan, Sichuan Province, Liangshan 615000, China)

机构地区：[1]凉山州第一人民医院,四川省西昌市615000

出　　处：《临床合理用药杂志》2017年第10期14-15,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的观察有创及无创序贯性机械通气治疗慢性阻塞性肺疾病(COPD)所致严重呼吸衰竭的疗效。方法将256例COPD所致严重呼吸衰竭患者随机分为2组,每组128例。试验组采用有创及无创序贯性机械通气的方法,对照组采用有创机械通气的方法,比较2组治疗结果。结果试验组住院时间、有创通气时间、病死率及呼吸机相关性肺炎(VAP)发生率均低于对照组,差异均有统计学意义(P<0.05)。治疗后,2组患者的呼吸频率、心率、动脉氧分压(Pa O2)、动脉二氧化碳分压(Pa CO2)及p H相比,差异均无统计学意义(P>0.05)。结论有创及无创序贯性机械通气治疗COPD所致严重呼吸衰竭的临床效果较好,使患者的各项指标均得到明显改善,应用前景广阔。Objective To observe the effect of invasive and non-invasive sequential mechanical ventilation in the treatment of chronic obstructive pulmonary disease（ COPD） effect caused by severe respiratory failure. Methods 256 patients with COPD induced by severe respiratory failure were divided into two groups randomly,128 cases in each group. The experimental group was treated with invasive and non-invasive sequential mechanical ventilation method,and the control group was given invasive ventilation. The clinical effect were compared between the two groups. Results Hospitalization time,ventilation time,the mortality rate and the incidence of VAP of experimental group was higher than that in control group（ P〈0. 05）. After treatment,respiratory rate,heart rate,Pa O2,Pa CO2 and p H between two groups had no obvious differences（ P〉0. 05）. Conclusion The clinical effect of invasive and non-invasive sequential mechanical ventilation in the treatment of severe respiratory failure caused by COPD is better,which can improve the indexes of the patients.

关 键 词：有创及无创序贯性机械通气 慢性阻塞性肺疾病 呼吸衰竭 

分 类 号：R563[医药卫生—呼吸系统]