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作 者:彭建铁 PENG Jian-tie.(Guangdong Huizhou City Boluo County Maternal and Child Health Care Hospital, Huizhou 516100, China)
出 处:《中国实用医药》2017年第7期30-32,共3页China Practical Medicine
基 金:惠州市科技计划项目(项目编号:20150804)
摘 要:目的探索超声检测宫颈长度(CL)及宫颈分泌物检测胎儿纤维连接蛋白(fFN)对早产预测的临床价值。方法 80例具有早产高危因素的孕妇为本次研究的对象,全部孕妇均于24~35周接受经阴道超声检查CL,采集宫颈分泌物检测fFN,追踪妊娠结局。结果 CL>30 mm组早产率13.04%,15~30 mm组早产率为34.78%,<15 mm组早产率为72.73%,三组早产情况比较,差异有统计学意义(P<0.05);在同一宫颈长度组中,fFN阳性组孕妇早产率明显高于阴性组(P<0.05);CL+fFN检测对早产的阳性预测值明显高于CL检测(P<0.05)。结论 CL和fFN检测的联合应用有助于临床医师对早产风险进行评估预测,从而根据风险的大小采取妊娠期的早期干预措施,保障母婴安全。Objective To investigate clinical value by cervical length (CL) ultrasound detection combined with fetal fibronectin (fFN) detection in cervical secreta in prediction of premature delivery. Methods There were 80 pregnant women with high risk of premature delivery as study subjects, and they all received CL ultrasound detection in 24-35 weeks. Their cervical secreta were taken for fFN detection, and pregnancy outcomes were traced in all patients. Results Premature delivery rate was respectively 13.04% in CL 〉30 mm group, 34.78% in 15~30 mm group and 72.73% in 〈15 mm group. The difference of premature delivery had statistical significance in the three groups (P〈0.05). Within each group of the same cervical length range, positive group had obviously higher premature delivery rate than negative group (P〈0.05). CL+fFN detection had much higher positive predictive value than CL detection (P〈0.05). Conclusion Combined application of CL and fFN detection is helpful for evaluation and prediction of premature delivery risks, in order to apply early intervention measures on the basis of risk level to guarantee maternal and infantile safety.
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