829例婴幼儿腹泻轮状病毒抗原检测分析  

Detection and analysis of rotavirus antigen in 829 cases of infantile diarrhea

作　　者：郭文丽[1] 郭予和 朱锦宏[2] 

机构地区：[1]深圳市宝安区人民医院检验科,广东深圳518101 [2]广州医科大学附属第二医院检验科,广东广州510260

出　　处：《热带医学杂志》2017年第3期400-401,404,共3页Journal of Tropical Medicine

基　　金：广州市医药卫生科技项目(20141A011082)

摘　　要：目的对婴幼儿腹泻患者进行粪便A组轮状病毒抗原检测,以了解A组轮状病毒(RV-A)感染情况及流行病学特征,为临床诊断提供依据。方法收集广州医科大学附属第二医院2014年1月至2015年12月因腹泻就诊的门诊和住院患儿粪便标本,采用胶体金免疫层析法检测A组轮状病毒。结果在829例患儿粪便标本中共检出RV-A阳性175例,阳性率为21.1%。全年均能检出RV-A阳性,以秋季阳性检出率最高,占全年阳性率的81.7%。不同性别腹泻患儿的阳性检出率差异无统计学意义(P>0.05);不同年龄组中以0.5~1岁和1~2岁组的阳性检出率最高,差异有统计学意义(P<0.05)。结论 A组轮状病毒是婴幼儿腹泻的重要病原体,以秋季高发,提示临床加强腹泻婴幼儿粪便中RV-A检测,对临床早诊断、早治疗和预防并发症有重要意义。Objective To detect the antigen of rotavirus A in stool of patients with diarrhea in our hospital or outpatient clinic in order to understand the infection status and epidemiological characteristics of rotavirus A （RV-A） , and provide evidence for clinical diagnosis. Methods The stool samples of patients with diarrhea in the Second Affiliated Hospital of Guangzhou Medical University from January 2014 to December 2015 were collected, and the A group rotavirus was detected by immune colloidal gold chromatography. Results 175 cases of A group were detected in stool samples from 829 children , with a positive rate of 21.1%. RV-A was detected in the whole year, with the highest positive rate in autumn, accounting for 81.7% of the whole year. There was no significant difference in the positive rate of children with diarrhea in different sex （P〉0.05）. There was significant difference of the positive detection rates between age group 0.5-1 years old and 1~2 years old. Conclusion A group rotavirus is an important pathogen of infantile diarrhea. The high incidence of diarrhea was in Autumn. RV-A detection should be strengthened for infants with diarrhea. A prompt clinical diagnosis is important for early treatment and prevention of complications.

关 键 词：A组轮状病毒 婴幼儿腹泻 粪便检测 

分 类 号：R512.5[医药卫生—内科学]