针刺、耳穴贴压联合二甲双胍治疗肥胖型多囊卵巢综合征不孕症临床观察  

Clinical Observation of Acupuncture Combined with Auricular Point Sticking for Obesity PCOS

作　　者：代晓峰[1] 

机构地区：[1]华亭县人民医院,甘肃华亭744100

出　　处：《新中医》2017年第4期128-131,共4页New Chinese Medicine

摘　　要：目的:观察针刺、耳穴贴压联合二甲双胍治疗肥胖型多囊卵巢综合征不孕症临床疗效。方法:将98例患者依照随机数字表法随机分为2组,对照组48例采用二甲双胍联合克罗米芬治疗,观察组50例在对照组治疗方案的基础上联合针刺及耳穴贴压治疗,观察比较2组卵巢体积、促卵泡生成素(FSH)、促黄体生成素(LH)等内分泌指标、HOMA法胰岛素抵抗指数(HOMA-IR)、空腹胰岛素(FIN)及总胆固醇(TC)、低密度酯蛋白(LDL-C)及甘油三酯(TG)等血脂水平改善情况,比较2组排卵率、妊娠率。结果:治疗后,2组卵巢体积水平、LH水平均降低,且观察组改善更明显,2组治疗前后比较、2组间比较,差异均有统计学意义(P<0.05);对照组FSH水平降低,观察组则升高,2组组间比较,差异有统计学意义(P<0.05)。治疗后,2组TG、TC、LDL-C均降低,治疗前后比较,差异均有统计学意义(P<0.05),观察组与对照组比较,差异均有统计学意义(P<0.05)。治疗后,患者FIN、HOMA-IR均降低,且观察组均改善更明显,差异均有统计学意义(P<0.05)。2组妊娠率及排卵率分别比较,差异均有统计学意义(P<0.05)。结论:针刺加耳穴贴压治疗肥胖型多囊卵巢综合征不孕症疗效良好,能调节糖脂指标、内分泌指标,提高胰岛素敏感性及排卵率、妊娠率,优于常规西药治疗。Objective： To observe the clinical effect of acupuncture combined with auricular point sticking for Obesity polycystic ovarian syndrome（PCOS）. Methods： Divided 98 patients into two groups randomly, the control group was given metformin combined with clomiphene, and the observation group was given acupuncture combined with auricular point sticking based on the treatment of the control group. Observed and compared the endocrine indexes like ovarian volume, follicle stimulating hormome（FSH）, luteinizing hormone（LH）, and improvement of blood lipid level like HOMA insulin resistance index （Homa-IR）, fasting insulin（FIN）, total cholesterol（TC）, Low-density lipoprotein（LDL-C）, triglyceride（TG） of the two groups, and compared the ovulation rate and pregnancy rate. Results： After treatment, level of ovarian volume and LH of the two groups were both decreased, and the improvement of the observation group was more significant, the difference being significant（P〈 0.05）. FSH level was decreased in the control group, but was increased in the observation group, the difference being significant（P〈 0.05）. After treatment, TG, TC and LDL-C of the two groups were all decreased, comparing with those before treatment, the difference being significant（P〈 0.05） , and the difference between the two groups being significant（P〈 0.05）. After treatment, FIN and HOMA-IR of the two groups were both decreased, but improvement of the observation group was more obvious, the difference being significant（P〈0.05）. Compared ovulation rate and pregnancy rate of the two groups respectively, the difference being significant（P〈 0.05）. Conclusion. Acupuncture combined with auricular point sticking has good clinical efficacy, can regulate glycolipid index and endocrine index and improve insulin sensitivity, ovulation rate and pregnancy rate, which has better effect than routine treatment in treating obesity PCOS infertility.

关 键 词：肥胖型多囊卵巢综合征 不孕症 针刺 耳穴贴压 二甲双胍 促卵泡生成素(FSH) 促黄体生成素(LH) HOMA法胰岛素抵抗指数(HOMA-IR) 

分 类 号：R711.75[医药卫生—妇产科学]