菱属植物化学成分与生物活性的研究进展  

A Research Progress on the Chemical Constituents and Biological Activity of Trapa L.

作　　者：赵小芳[1] 李娟[1,2] 徐博[1] 唐敏[1] 熊斯[1] 李顺祥[1,2] 

机构地区：[1]湖南中医药大学药学院,长沙410208 [2]湖南省中药活性物质筛选工程技术研究中心,长沙410208

出　　处：《世界科学技术-中医药现代化》2017年第2期283-288,共6页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家中医药管理局"药用植物学"重点学科课题(国中医药发[2009]30号);湖南省"中药学"重点学科(湘教通[2011]76号);湖南省高校科技创新团队(湘教通[2010]212号)

摘　　要：中国菱属植物资源较为丰富,菱角食药用历史悠久。菱属植物中主要的化学成分为萜类、甾醇、酚酸类及黄酮类等化合物,目前对其生物活性的研究比较深入,有降血糖、抗氧化、抗肿瘤、抗菌和免疫调节等活性,已有初步研究的生物活性包括降低血管内皮生长因子(VEGF)表达、抑制H2O2诱导的人脐静脉内皮细胞损伤、诱导He La细胞凋亡、镇痛、保肝、抗动脉粥样硬化和驱虫。本文对菱属植物的化学成分及生物活性进行了综述,以期对菱属植物的开发利用提供依据。China boasts for its abundant resources of Trapa L. The fruit of Trapa has been given high edible and medicinal values so far. Trapa L. plants mainly contain terpenoids, sterols, phenolic acids and flavonoids. Current studies profoundly analyzed the biological activities on hypoglycemic, anti-oxidation, anti-tumor, antibacterial and immunomodulatory effects of it. Some preliminary studies over biological activities included the effects on reducing the expression of vascular endothelial growth factor（VEGF）, the inhibition of H_2O_2-induced injury of human umbilical vein endothelial cells,inducing He La cell apoptosis, analgesia, liver protection, anti-atherosclerosis and deworming. This paper reviewed literature on the chemical constituents and biological activities of Trapa L for the provision of a reference for the exploration and utilization of Trapa L.

关 键 词：菱属 化学成分 生物活性 降糖 

分 类 号：R931.6[医药卫生—生药学]