全麻诱导行气管插管和喉罩置入对定量药物脑电图α1频段的影响  

Effects of Tracheal Intubation and Laryngeal Mask on the α1-band of Quantitative Pharmacoelectroencephalography during General Anesthesia Induction

作　　者：李阳[1] 曹悦悦 麻婷婷[1] 王宏玉[1] 朱俊超[1] 

机构地区：[1]中国医科大学附属盛京医院麻醉科,沈阳110004

出　　处：《中国医科大学学报》2017年第4期357-359,362,共4页Journal of China Medical University

摘　　要：目的对比全麻诱导时行气管插管和喉罩置入对定量药物脑电图(QPEEG)α1频段的影响。方法选取择期全麻手术患者40例,随机分为气管插管组(T组)和喉罩置入组(L组),每组20例。分别记录2组患者麻醉诱导前(T0)、诱导后(T1)、插入气管插管或喉罩置入后(T2)的心率(HR)、平均动脉压(MAP)和QPEEG,利用功率谱分析技术计算QPEEG的α1频段的功率百分比。结果与T0时刻比较,T1时刻2组患者的HR、MAP和大部分脑区的α1频段百分比均有所下降(P<0.05);与T1时刻相比,T2时刻T组HR、MAP和α1频段百分比均有所上升(P<0.05),L组则无明显改变(P>0.05)。结论与喉罩置入相比,气管插管对循环系统的刺激更为强烈,并可引起QPEEG的α1频段功率百分比增加,提示QPEEG的α1频段可作为反映刺激强弱的指标。Objective To compare the effects of tracheal intubation（TI）and laryngeal mask（LM）during general anesthesia（GA）induction on the α1-band of quantitative pharmaco-electroencephalography（QPEEG）. Methods Fortypatients undergoing GA were randomly divided into two groups：group T included 20 patients who received TI and group L included 20 who received a LM. Parameters like heart rate（HR）,mean arterial pressure（MAP）,and QPEEG were recorded before anesthesia induction（T0）,after induction（T1）,and after intubating the cannula or LM（T2）.Using power-spectrum analysis,we calculated the power percentage of the α1-band of QPEEG. Results The HR,MAP,and power percentage of the α1-band in most areas of the brain were lower at T1 than at T0（P 〈 0.05）in both groups. Moreover,the HR,MAP,and α1-band power percentage were higher at T2 than at T1（P 〈 0.05）in group T,whereas they showed no significant change at T2（P 〉 0.05）in group L.Conclusion TI is stronger than LM for stimulating the circulatory system. Moreover,TI may cause an increase in the power percentage of the α1-band of QPEEG. This finding suggests that the α1-band power percentage of QPEEG can be an effective means of monitoring stimulation.

关 键 词：气管插管 喉罩 定量药物脑电图 α1频段 

分 类 号：R614.2[医药卫生—麻醉学]