胸痹心痛方剂的组方规律挖掘分析  

Mining Analysis of Regularity of Prescriptions for Thoracic Obstruction and Cardiodynia

作　　者：王倩[1] 姚耿圳[2] 潘光明[2] 黄晶一 邹旭[2] 

机构地区：[1]广州中医药大学第二临床医学院,广东广州510405 [2]广东省中医院,广东广州510120

出　　处：《辽宁中医杂志》2017年第4期683-686,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：广东省省级科技计划项目(2014A020212645);中医药强省专项-2015广东省名中医师承项目

摘　　要：目的:基于中医传承辅助系统(V2.5)软件,分析挖掘《中医方剂大辞典》中胸痹心痛方剂的组方用药规律。方法:筛选、整理《中医方剂大辞典》中治疗胸痹心痛的方剂,并基于中医传承辅助系统软件,应用关联规则、改进的互信息法、复杂系统熵聚类等挖掘方法对数据进行挖掘。结果:通过对纳入的388首处方进行分析,处方中共出现275味中药,其中最高频药物为桂心和当归。挖掘出22个核心处方和7个新方组合。结论:利用中医传承辅助系统,挖掘分析胸痹心痛方剂的组方规律,并将其规律直观化,可以为中医治疗胸痹心痛提供新的启发和参考。Objective ： To analyze the regularity of prescriptions for thoracic obstruction and cardiodynia from Prescription Dic- tionary of Traditional Chinese Medicine based on Traditional Chinese Medicine inheritance support system （TCMISS V2.5 ）. Methods：The prescriptions used for thoracic obstruction and cardiodynia from the Prescription Dictionary of Traditional Chinese Medicine were selected and the medical information was standardized to establish a database. And then the data was mined by the use of association rule, improved mutual information algorithm and clustering based on TCMISS. Results ： By the analysis, it includ- ed 388 prescriptions,275 kinds of herbs, of which the most frequent herbs were cortex cinnamomi and angelica. Meanwhile,22 core groups and 7 new prescriptions were mined. Conclusion ： The regularity of the prescriptions for thoracic obstruction and cardio- dynia were clarified and visualized by the TCMISS, which provided the reference for the clinical application in the treatment of thoracic obstruction and cardiodynia.

关 键 词：中医方剂大辞典 胸痹心痛 组方规律 挖掘分析 中医传承辅助系统 

分 类 号：R256.22[医药卫生—中医内科学]