仙灵骨葆胶囊治疗绝经期骨质疏松症临床研究  

The Clinical Research into menopausal osteoporosis Treated with Xianlinggubao Capsules

作　　者：宋小梅 

机构地区：[1]北京市朝阳区亚运村社区卫生服务中心,北京100100

出　　处：《河南中医》2017年第4期686-688,共3页Henan Traditional Chinese Medicine

基　　金：北京市中医药科技项目(编号:JJ2001-33)

摘　　要：目的:观察仙灵骨葆胶囊治疗绝经期骨质疏松症的临床疗效。方法:选择本院接收的绝经后骨质疏松症患者62例,随机法分为观察组和对照组,每组各31例。对照组给予益钙宁,肌肉注射,观察组在对照组的基础上口服仙灵骨葆胶囊。观察两组患者的临床疗效及治疗前后骨密度变化情况。结果:观察组有效率为90.3%,对照组有效率为67.7%,两组患者临床疗效比较,差异具有统计学意义(P<0.05)。治疗后两组患者的L2~4和股骨大转子骨密度均有显著增加(P<0.05),观察组L_(2~4)、股骨颈及股骨大转子的骨密度均明显高于对照组,差异具有统计学意义(P<0.05)。治疗后观察组血钙(2.90±0.25)mmol·L^(-1)、血磷(1.93±0.22)mmol·L^(-1)、血清磷酸酶(89.72±11.23)IU·L^(-1),与对照组比较,差异具有统计学意义(P<0.05)。结论:仙灵骨葆胶囊辅助益钙宁对于绝经期骨质疏松症患者疗效良好。Objective： To observe the clinical curative effect of Xianlinggubao Capsules（ XLGBC） on menopausal osteoporosis.Methods： Sixty-two patients with menopausal osteoporosis who were treated in our hospital were chosen as the research subjects,and randomly divided into the observation group and the control group,with 31 cases in each group. The ones in the control group were given Elcitonin for intramuscular injection,while the ones in the observation group were added XLGBC for oral administration based on the treatment of the control group. Then the clinical efficacies of the two groups and the changes of bone mineral density before and after the treatment were observed. Results： The effective rate of the observation group was 90. 3%,while that of the control group was 67. 7%,and the difference in the clinical efficacy of the two groups was statistically significant（ P〈0. 05）. After the treatment,the two groups＇ L（2-4） lumbar spine and trochanter BMD increased significantly（ P〈0. 05）,the bone density of the observation group＇s L（2-4）,femoral neck and trochanter of femur were significantly higher than those of the control group,and all the differences were statistically significant（ P〈0. 05）. After the treatment,the observation group＇s serum calcium was（ 2. 90 ±0. 25） mmol/L,blood phosphorus was（ 1. 93 ± 0. 22） mmol/L,serum phosphatase was（ 89. 72 ± 11. 23） IU/L,compared with the control group,the differences were statistically significant（ P〈0. 05）. Conclusion： Xianlinggubao Capsulea assisting Elcitonin has a good curative effect on patients with menopausal osteoporosis.

关 键 词：绝经期骨质疏松症 仙灵骨葆胶囊 益钙宁 

分 类 号：R274.98[医药卫生—中西医结合]