卵巢动脉血流指数对体外受精-胚胎移植患者妊娠结局的影响  

Influence of ovarian artery blood flow index on pregnancy outcomes of patients undergoing in vitro fertilization-embryo transfer

作　　者：夏燕[1,2] 孔黎娜 冯颖 魏兆莲[1] 

机构地区：[1]安徽医科大学第一附属医院生殖医学中心,合肥市230022 [2]妇幼保健院,乌鲁木齐市830001

出　　处：《实用医学杂志》2017年第7期1124-1126,共3页The Journal of Practical Medicine

摘　　要：目的:探讨卵巢动脉血流指数对体外受精-胚胎移植患者妊娠结局的影响。方法:选取2014年2月至2016年4月进行体外受精-胚胎移植的不孕患者136例为研究对象,根据是否妊娠分为妊娠组与未妊娠组,经阴道B超对两组患者人绒毛促性腺激素(HCG)日和月经第2天(M2)的卵巢动脉血流阻力指数(RI)、搏动指数(PI)及其动脉舒张压血流速度高低比值(S/D)进行监测。并对两组血流指数的差异进行分析。结果:与未妊娠组对比,妊娠组患者M2日RI、PI及S/D降低,差异有统计学意义(P<0.05),HCG日RI、PI也显著降低,差异有统计学意义(P<0.05),S/D无明显变化,差异无统计学意义(P>0.05)。与同组M2日对比,妊娠组患者HCG日RI及PI均明显降低,未妊娠组患者HCG日RI及PI也明显降低,差异有统计学意义(P<0.05),S/D对比无差异(P>0.05)。结论:卵巢动脉血流RI及PI与卵巢储备功能存在密切联系,是预测体外受精-胚胎移植结局的有效指标,能够为体外受精-胚胎移植技术的前期准备及治疗提供更科学的依据。Objective To investigate the influence of ovarian arterial blood flow index on pregnancy outcomes in patients undergoing in vitro fertilization and embryo transfer（IVF-ET）. Methods Totally 136 infertile patients undergoing IVF-ET from February 2014 to April 2016 were divided into pregnant group and non-pregnant group. The monitoring through transvaginal B of two groups for chorionic gonadotropin （HCG） day and ovarian artery resistance index （RI）, pulsatility index （PI） and umbilical artery diastolic flow velocity height ratio （S/D） on 2nd day of menstruation （M2） was conducted. The difference of blood flow indexes in two groups was analyzed. Results Compared with those in non-pregnant group, HI, PI and S/D in pregnant group were decreased on M2, and the difference was statistically significant （P 〈 0.05 ）. RI and PI were also decreased significantly on HCG day, and the difference was statistically significant （P 〈 0.05 ） , but S/D showed no significant changes （P 〉 0.05 ）. RI and PI decreased significantly on HCG day in two groups （ P 〈 0.05 ） when compared with those on M2, but in non-pregnant group, the comparison of S/D on HCG clay showed no statistical significance （P 〉 0.05 ）. Conclusions There is close relationship among RI and PI of ovarian artery and ovarian reserve function. RI and PI are effective indexes to predict outcomes in IVF-ET, and provide scientific basis for the preparation and treatment for IVF-ET.

关 键 词：体外受精一胚胎移植 卵巢动脉 血流指数 妊娠结局 

分 类 号：R714.8[医药卫生—妇产科学]