体型指数与炎症异常的关系  

Research on the relationship between a body shape index and abnormal inflammation

作　　者：何森[1] 李春慧 郑翼[1] 崔凯军[1] 陈晓平[1] 

机构地区：[1]四川大学华西医院心脏内科,成都610041 [2]攀枝花钢铁(集团)公司职工总医院心脏内科,四川攀枝花617023

出　　处：《华西医学》2017年第4期515-519,共5页West China Medical Journal

基　　金：国家科技部"十一五"科技支撑项目(2006BAI01A01)

摘　　要：目的探讨体型指数(a body shape index,ABSI)与炎症异常的关系。方法 2007年5月,在成都市成华区进行了横断面调查研究,采用随机方法抽样人群,共有651人纳入最终分析,主要评估ABSI等指标与炎症异常的关系,其中炎症异常定义为高敏C反应蛋白≥3 mg/L。结果 logistic回归分析提示体质量指数(body mass index,BMI)、腰围及ABSI与炎症异常独立相关。在识别炎症异常时,腰围的能力最佳,受试者工作特征曲线下面积(area under the receiver operating characteristic curve,AROC)为0.627[95%置信区间(0.564,0.689)],随后是BMI及ABSI,AROC分别为0.609及0.608。进一步分析提示ABSI联合BMI时可以改善BMI识别炎症异常的能力,AROC从0.609增加至0.646;ABSI联合腰围也可以改善腰围对于炎症异常的识别能力,但AROC仅从0.627增加至0.631。结论在中国人群中,ABSI与炎症异常独立相关,但ABSI识别炎症异常的能力较差,并不优于BMI及腰围;此外,ABSI可以进一步改善BMI及腰围识别炎症异常的能力,特别是对于BMI。该结论是否存在种族差异,需要进一步研究。Objective To investigate the relationship between a body shape index （ABSI） and abnormal inflammation. Methods In May 2007, a cross-sectional study was conducted among 651 individuals by random sampling method in an urban community located in Chenghua district of Chengdu. We mainly assessed the relationship between ABSI and abnormal inflammation, which was defined as high sensitive C-reactive protein equal to 3 mg/L or higher. Results Logistic regression analysis showed that body mass index （BMI）, waist circumference （WC） and ABSI were independently associated with abnormal inflammation. For identifying abnormal inflammation, WC had the best discriminatory power with the area under the receiver operating characteristic curve （AROC） was 0.627 [95% CI （0.564, 0.689）], followed by BMI （AROC： 0.609） and ABSI （AROC： 0.608）. In addition, combination with ABSI could improve the discriminatory power of BMI for abnormal inflammation, and AROC increased from 0.609 to 0.646. Combination with ABSI could also improve the discriminatory power of WC for abnormal inflammation, and AROC only increased from 0.627 to 0.631. Conclusions In the general Chinese population, ABSI is independently associated with abnormal inflammation, but the discriminatory power is poor, no better than BMI and WC. Furthermore, combination with ABSI can improve the discriminatory power of BMI and WC for abnormal inflammation, especially for BMI. Further studies about ethnic specificities of ABSI are needed.

关 键 词：体型指数 体质量指数 腰围 炎症异常 

分 类 号：R364.5[医药卫生—病理学]