热疗对原发性免疫性血小板减少症的疗效观察  

To observe the effect of hyperthermia on immune thrombocytopenia

作　　者：李志改[1] 李秀芹[1] 张虎田[1] 陈建林[1] 

机构地区：[1]东海县人民医院,江苏连云港222300

出　　处：《辽宁医学杂志》2017年第2期25-27,共3页Medical Journal of Liaoning

摘　　要：目的观察热疗对免疫性血小板减少症患者的疗效;方法选择ITP患者50例,随机分成治疗组及对照组,治疗组采用热疗和大剂量地塞米松治疗,对照组仅采用大剂量地塞米松治疗,观察疗效及血小板恢复正常时间及倍增时间。结果总有效率(OR)对照组(88%)与治疗组(92%)之间无统计学差异,完全缓解率(CR)对照组(80%)高于治疗组(52%),两组之间有统计学差异(P<0.05);血小板计数达到正常值的时间,治疗组(9.28±0.96)天,早于对照组(11.56±1.34)天;血小板计数倍增时间治疗组(5.81±0.67)天,早于对照组(7.84±0.89)天,两组比较均存在统计学意义(P<0.05)。结论热疗可缩短ITP患者血小板升到正常值的时间,增加完全缓解率,降低出血风险,值得临床应用。Objective To observe the effect of hyperthermia on primary immune thrombocytopenia.Methods selected 50 patients,divided into two groups randomly,the patients in treatment group were treated with HD-DXM and hyperthermia,the patients in control group were treatewith HD-DXM only,observed the changes of PLT before and after hyperthermia,recorded the time of PLT returning to normal and doubling time Results The time of PLT returning to normal and doubling in treatment group were shorter than in the control group （P〈0.05）;the OR had no significant difference between control group（88%） and treatment group（92%）;the CR rate was higher in treatment group （80%）than in the control group（52%） （P〈0.05）.Conclusion Hyperthermia enhanced hematopoietic function,shorten the time of PLT returning to normal and double,increase the CR rate;it can reduce the risk of bleeding and be worth to applicate in clinic.

关 键 词：热疗 原发性免疫性血小板减少症 有效率 

分 类 号：R558.2[医药卫生—血液循环系统疾病]