脊髓电刺激治疗消化道动力障碍疾病的研究进展  

Research Progress of Spinal Cord Stimulation to Treat Gastrointestinal Motility Disorder Diseases

作　　者：万新月[1] 刘苗[1] 邓涛[1] WAN Xinyue LIU Miao DENG Tao.(Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, Chin)

机构地区：[1]武汉大学人民医院消化内科,武汉430060

出　　处：《医学综述》2017年第8期1599-1603,共5页Medical Recapitulate

摘　　要：消化道动力障碍疾病往往需要长期服用药物,却仅能使部分患者受益,人们一直在寻找一种低侵入性而有效的治疗方法。脊髓电刺激术已经在临床上用于治疗慢性疼痛,其机制与降低交感神经兴奋性有关,脊髓电刺激亦能通过降低交感神经兴奋、提高迷走神经兴奋性而刺激胃肠蠕动,加快大鼠胃和小肠排空,降低内脏敏感性、减弱内脏反射,对于功能性消化不良、肠易激综合征、术后肠梗阻、糖尿病胃轻瘫等疾病有一定治疗作用,从而为治疗消化道动力障碍疾病提供了新方向。Most of patients who suffered with gastrointestinal motility disorder disease needed long-term use of medications. But only some of them benefited from this. People are keeping to find a less invasive and more effective method to treat this disease. As we know spinal cord stimulation （SCS） have been used to treat chronic pain in clinic. The mechanisms was involved with reduced the excitability of sympathetic nerves. But recent studies have shown that SCS can also enhance gastrointestinal tract motility, accelerate gastric emptying and intestinal transit and reduce the visceral sensitivity by subsiding sympathetic activity and increasing excitability of the vagus nerve. These researches showed SCS was helpful to treat functional dyspepsia, irritable bowel syndrome, postoperative ileus, and diabetic gastroparesis. So, SCS give us a new idea to treat ~astrointestiual motility disorder disease.

关 键 词：脊髓电刺激 消化道动力障碍性疾病 交感神经活性 

分 类 号：R246.1[医药卫生—针灸推拿学]