透明敷贴在异基因造血干细胞移植术后并发皮肤GVHD患者PICC导管维护中的应用  

Application research on dressings for patients with skin GVHD after allogeneic hcmatopoietic stem cell transplantation in PICC catheter maintenance

作　　者：毛凌[1] 陈凤姣[1] 张川莉[1] 

机构地区：[1]四川大学华西医院血液内科,成都610041

出　　处：《中华现代护理杂志》2017年第1期64-66,共3页Chinese Journal of Modern Nursing

摘　　要：【摘要】目的比较两种规格透明敷贴在异基因造血干细胞移植（Allo．HSCT）术后并发皮肤急性移植物抗宿主病（GVHD）患者PICC导管维护中的应用效果。方法回顾性分析四川大学华西医院收治的Allo—HSCT术后并发皮肤GVHD且留置PICC患者86例，选取2012年3月-2014年1月使用规格10cm×12cm敷贴的42例患者为对照组，2014年3月-2016年1月使用规格6cm×7cm敷贴的44例患者为观察组。在进行PICC维护时，比较两组导管维护效果。结果两种规格敷贴导管固定有效性、导管相关感染以及敷贴更换间隔时间比较，差异无统计学意义（P〉0．05）；观察组医用粘胶相关皮肤损伤低于对照组，差异有统计学意义（P〈0．05）。结论进行PICC维护时，尺寸较小的透明敷料（6cm×7cm）具有较好的安全性和舒适性，且成本效益更佳，适用于Allo．HSCT术后并发皮肤GVHD患者的PICC导管维护。Objective To compare the effects of two kinds of transparent dressings for patients with skin graft-versus-host disease （GVHD） after allogeneic hcmatopoietic stem cell transplantation （Allo-HSCT） in PICC catheter maintenance. Methods Retrospective analysis was conducted among 86 patients who had complicated skin GVHD after Allo-HSCT and used PICC catheter. We selected 42 patients who used dressings of 10 cm x 12 cm from March 2012 to January 2014 as the control group, and selected 44 patients who used dressings of 6 cm x 7 cm from March 2014 to January 2016 as the observation group. During the maintenance of PICC catheters, the maintenance effect of catheters in two groups were analyzed. Results There was no significant difference between two groups in the effect of catheter maintatence, catheter-related infection, and the dressing replacement interval （P 〈 0.05）. While the medical adhesive related skin injury of the observation group was significantly lower than that of the control group （P 〈 0.05）. Conclusions During the maintenance of PICC catheters, the transparent dressing of 6 cm x 7 cm is much safer, more comfortable with less costs. It is esoeciallv suitable for the patients with skin GVHD after Allo-HSCT.

关 键 词：造血干细胞移植 移植物抗宿主病 敷贴 经外周穿刺中心静脉置管 

分 类 号：R473.5[医药卫生—护理学]