小儿支气管肺炎伴血小板增多的临床特征及炎症因子的变化情况分析  

Analysis of clinical features and changes of inflammatory factors in children with bronchial pneumonia associated with increased platelet count

作　　者：张向峰[1] 常会娟[1] 张小宁[1] 余燕娟 李晓燕[1] 靳秀红[1] 

机构地区：[1]郑州市儿童医院呼吸内科,450000

出　　处：《中国实用医刊》2017年第7期90-92,共3页Chinese Journal of Practical Medicine

摘　　要：目的 对小儿支气管肺炎伴血小板增多的临床特征及炎症因子变化进行深入分析.方法 选择2015年2月至2016年2月支气管肺炎患儿100例作为本次研究对象,依照血生化检测结果,58单纯性支气管肺炎患儿作为对照组,42例支气管肺炎伴血小板增多患儿为对照组,对两组患儿的免疫功能、临床治疗及炎性因子变化等进行比较分析.结果 两组患儿在年龄、喘息、呼吸困难、住院时间、并发症发生率及病死率等方面比较差异均有统计学意义（P〈0.05）;研究组患儿肿瘤坏死因子（TNF-α）、白细胞介素（IL）-6、C-反应蛋白（CRP）等炎性因子水平均高于对照组,差异均有统计意义（P〈0.05）.结论 小儿支气管肺炎伴血小板增多病情较重,通过血液检测可将血小板增多、炎性因子变化作为病情发展的参考指标,在临床诊疗中有重要意义.Objective To analyze the clinical features of children with bronchial pneumonia and the changes of inflammatory factors in the clinical features and the changes of inflammatory factors.Methods From February 2015 to February 2016, 100 cases of bronchial pneumonia were selected as the research objects, in accordance with the biochemical results, 58 patients with simple bronchial pneumonia as control group, 42 cases of bronchial pneumonia with platelet as the control group.The free immune function, clinical treatment and inflammatory factor changes were compared.Results There were significant differences in age, wheezing, dyspnea, length of stay, incidence of complications and mortality in the two groups （P〈0.05）.The levels of TNF, IL, CRP and other inflammatory factors in the study group were all higher than those in the control group, the differences were significant （P〈0.05）.Conclusions The condition of children with bronchial pneumonia with thrombocytosis is more serious, through the blood test, thrombocytosis inflammatory factor changes can be used as a references for the development of the disease, and has important significance in clinical diagnosis and treatment.

关 键 词：小儿支气管肺炎 血小板增多 临床特征 炎症因子 

分 类 号：R725.6[医药卫生—儿科]