原发性高血压老年患者高尿酸血症的影响因素研究  

Influencing factors of hyperuricemia in elderly patients with hypertension

作　　者：胡烨文[1] 王世奇[1] 陈晓敏[1] 王建[1] 叶红华[1] 

机构地区：[1]宁波市第一医院心内科,315000

出　　处：《浙江医学》2017年第7期549-550,554,共3页Zhejiang Medical Journal

基　　金：宁波市科技计划项目(2011C51003)

摘　　要：目的研究高血压老年患者高尿酸血症的影响因素。方法选取2015年3月至2016年2月收治的原发性高血压患者97例,其中高血压合并高尿酸血症患者53例,将其作为合并组;另外44例不伴高尿酸血症的高血压患者,将其作为对照组。检查并比较两组患者的血尿酸、TC、TG、FPG、BMI、腰围、WHR等指标,采用logistic回归分析方式,分析上述指标与高尿酸血症的相关性,讨论该病症的具体影响因素。结果两组血尿酸、TC、TG以及FPG水平差异均有统计学意义(均P<0.05);两组BMI、收缩压、舒张压、腰围以及WHR差异均无统计学意义(均P>0.05)。logistic回归分析结果显示,患者的TC、TG水平,BMI值、腰围、WHR均为高血压老年患者患高尿酸血症的相关影响因素(均P<0.05)。结论血尿酸水平、TC、TG、BMI、腰围、WHR均为高血压老年患者的高尿酸血症的影响因素。Objective To study the influencing factors of hyperuricemia in elderly patients with hypertension.Methods Ninety seven elderly patients with essential hypertension were enrolled from our hospital on March 2015 to February 2016,including 53 patients complicated with hyperuricemia（study group） and patients without hyperuricemia（control group）.The blood uric acid,total cholesterol（TC）,triglyceride（TG） and fasting glucose（FPG） levels,body mass index（BMI）,waist circumference（WC） and waist to hip ratio（WHR） and other indicators were measured and compared in two groups.The correlation of hyperuricemia with above indicators was analyzed with logistic regression analysis.Results The mean levels ofTC,TG and FPG in study group were significantly higher than those in control group（all P〈 0.05）,while there were no significant differences in BMI,systolic blood pressure,diastolic pressure,WC and WHR between two groups（P 〉0.05）.Logistic regression analysis results showed that the TC,TG levels,BMI index,WC and WHR were influencing factors of hyperuricemia in elderly patients with hypertension（P = 0.041,0.039,0.036,0.008,0.029）.Conclusion The TC,TG,BMI index,waist circumference and waist to hip ratio are influencing factors ofhyperuricemia in elderly patients with hypertension.

关 键 词：高血压 高尿酸血症 影响因素 

分 类 号：R544.11[医药卫生—心血管疾病]