hsCRP、CysC水平对老年急性冠脉综合征诊断和病情预测的价值  

Diagnostic and predictive value of hsCRP and CysC levels for acute coronary syndrome in aged patients

作　　者：胡江乔[1] 皮林[1] 宋丽芬[1] 徐世莹[1] 贾博[1] 

机构地区：[1]北京市垂杨柳医院心内科,北京市100021

出　　处：《心血管康复医学杂志》2017年第2期165-167,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:研究高敏C反应蛋白(hsCRP)、胱抑素C(CysC)水平对老年急性冠脉综合征(ACS)诊断和病情预测的价值。方法:随机选择2013年12月~2015年9月期间,在我院进行治疗的ACS患者60例(ACS组),以及健康体检人员60例(健康对照组)。测定比较两组血清hsCRP、CysC水平,以及hsCRP异常率和CysC异常率。结果:与健康对照组比较,ACS组血清hsCRP[(3.02±1.13)mg/L比(7.95±2.38)mg/L]和CysC水平[(0.75±0.11)μg/ml比(1.35±0.43)μg/ml]显著升高,hsCRP异常率(0比13.33%)和CysC异常率(0比11.67%)也显著升高,P均<0.01。结论:对急性冠脉综合征患者血清高敏C反应蛋白和胱抑素C水平进行检测,可以对患者病情发生、发展以及预后进行有效的预测评估,为其诊断和防治提供有效的临床依据。Objective： To study diagnostic and predictive value of levels of high sensitive C reactive protein （hsCRP） and cystatin C （CysC） for acute coronary syndrome （ACS） in aged patients. Methods.. A total of 60 ACS patients （ACS group） treated in our hospital and 60 healthy subjects （healthy control group） undergoing physical examination during Dec 2013 to Sep 2015 were randomly selected. Serum levels of hsCRP and CysC, and abnormal rates of hsCRP and CysC were measured and compared between two groups. Results： Compared with healthy control group, there were significant rise in serum levels of hsCRP [ （3.02 ± 1.13） mg/L vs. （7.95 ± 2.38） mg/L] and CysC [ （0. 75 ± 0. 11） μg/ml vs. （1.35 ± 0. 43） μg/ ml], and abnormal rates of hsCRP （0 vs. 13.33%） and CysC （0 vs. 11.67%） in ACS group, P〈0.01 all. Conclusion： Serum hsCRP and CysC level measurements can effectively predict and assess occurrence, development and prognosis of disease in ACS patients, and provide clinical valid evidence for its diagnosis, prevention and treatment.

关 键 词：急性冠状动脉综合征 C反应蛋白质 半胱氨酸蛋白酶抑制剂 

分 类 号：R541.409[医药卫生—心血管疾病]