探究儿童抗生素相关性腹泻中药学干预的作用与价值  

Effect and Value of TCM Intervention in the Antibiotic Associated Diarrhea in Children

作　　者：孙谦[1] 路娜娜[2] 孙雯[3] 孙越[4] 李德军[1] 

机构地区：[1]济宁医学院附属医院静脉用药调配中心,山东济宁272019 [2]济宁市第一人民医院新生儿病房,山东济宁272011 [3]济宁医学院附属医院教学管理处,山东济宁272019 [4]济宁市第一人民医院静脉用药调配中心,山东济宁272011

出　　处：《中外医疗》2017年第8期1-3,共3页China & Foreign Medical Treatment

摘　　要：目的探究儿童抗生素相关性腹泻中药学干预的作用与价值。方法方便选取2015年2月—2016年2月期间,该院接受治疗的80例儿童抗生素相关性腹泻患儿作为研究对象,根据不同的治疗方法将所有患儿分为对照组(n=40)和观察组(n=40),对照组患儿采用西医治疗,观察组患儿在对照组的基础上采用中药学干预,观察分析两组患儿的治疗效果,干预后的相关腹泻发生率,大便次数,大便次数恢复时间,大便性状恢复时间,腹泻总疗程,腹泻程度积分,药物起效时间和APACHEⅡ积分。结果观察组患儿的治疗总有效率是95.00%明显高于对照组患儿的治疗总有效率是77.50%,观察组患儿干预后的相关腹泻发生率是7.50%(3/40),对照组患儿干预后的相关腹泻发生率是25.00%(10/40)(χ~2=4.875 6,P<0.05)。两组患儿的治疗效果,干预后相关腹泻发生率,大便次数,大便次数恢复时间,大便性状恢复时间,腹泻总疗程,腹泻程度积分,药物起效时间和APACHEⅡ积分比较差异有统计学意义(P<0.05)。结论在对照组的基础上采用中药学干预对儿童抗生素相关性腹泻患儿具有较大的意义,可有效提高患儿的治疗效果,降低患儿的相关腹泻发生率,减少患儿的大便次数,缩短患儿的大便次数恢复时间,大便性状恢复时间,腹泻总疗程和药物起效时间,降低患儿的腹泻程度积分和APACHEⅡ积分,为该病患儿的治疗提供较为科学的临床依据。Objective To study the effect and value of TCM intervention in the antibiotic associated diarrhea in children.Methods Convenient selection 80 cases of children with antibiotic associated diarrhea treated in our hospital from February2015 to February 2016 were selected and divided into two groups with 40 cases in each according to the different treatment methods,the control group were treated with western medicine,while the observation group adopted the TCM intervention on the basis of the control group,and the treatment effect of the two groups was observed and analyzed and the incidence rate of associated diarrhea,frequency of defecation,recovery time of defecation time,recovery time of stool property,total treatment course of diarrhea,diarrhea degree integration,drug onset time and APACHEⅡ integration after intervention were observed.Results The total treatment effective rate in the observation group was obviously higher than that in the control group,（95.00% vs 77.50%）,after intervention,the incidence rate of associated diarrhea after intervention in the observation group and the control group was respectively 7.50%（3/40） and 25.00%（10/40）（χ~2=4.875 6,P〈0.05）,and the differences in the treatment effect,incidence rate of associated diarrhea after intervention,stool frequency,recovery time of stool time,recovery time of stool property,total treatment course of diarrhea,diarrhea degree integral,drug onset time and APACHE Ⅱintegral after intervention had statistical significance（P〈0.05）.Conclusion The TCM intervention is of great significance to the children with antibiotic associated diarrhea on the basis of the control group,which can effectively improve the treatment effect,reduce the incidence rate of associated diarrhea,reduce the stool frequency,shorten the recovery time of stool frequency,recovery time of stool property,total treatment course of diarrhea and drug onset time and reduce the diarrhea degree integral and APACHEⅡ integral and provide the scientific clinical basis f

关 键 词：儿童抗生素相关性腹泻 中药学干预 临床作用 临床价值 

分 类 号：R5[医药卫生—内科学]