男性无精子症患者血清生殖激素水平与睾丸生精功能的相关性分析  

Correlation analysis of serum reproductive hormone levels and testicular spermatogenic function of male patients with azoospermia

作　　者：程国隆 宋荣 

机构地区：[1]昆明爱维艾夫医院男科,云南昆明650000 [2]昆明爱维艾夫医院妇科,云南昆明650000

出　　处：《中国当代医药》2017年第10期36-38,共3页China Modern Medicine

摘　　要：目的探讨男性无精子症患者血清生殖激素水平含量与睾丸生精功能的相关性分析。方法选取我院2013年3月~2016年3月期间确诊的144例患者,将其中94例无精子症患者为试验组,50例生育健康男性为对照组。试验组患者根据穿刺结果分为A组(穿刺无精子组)31例、B组(穿刺有精子组)63例。比较各组患者在精液常规、血清生殖激素水平的差异及其与睾丸生精功能的相关性。结果 A组FSH、LH明显高于对照组,而睾酮值低于对照组水平(P<0.05)。B组与对照组相比各激素水平无明显差异(P>0.05)。激素水平与睾丸生精功能呈现出负相关(FSH:r=-0.572,P=0.000;LH:r=-0.431,P=0.000),睾酮T与睾丸生精功能成正相关(r=0.313,P=0.014)。PRL、E2与睾丸生精功能无相关性。结论 FSH与无精子症有着密切的联系,可作为睾丸穿刺前的预判指标,对无精子症的治疗有着重要的意义,值得进一步的研究。Objective To explore correlation of serum reproductive hormone levels and testicular spermatogenic function of male patients with azoospermia.Methods 144 cases of patients who were diagnosed in hospital from March 2013 to March 2016 were selected,and 94 cases of patients with azoospermia were selected as experimental group and 50 cases of fertile heahhy men were selected as the control group.The patients in the experimental group were divided into group A （31 cases without sperm group） and group B （63 cases with sperm group）.The difference of semen routine and serum reproductive hormone level,and the correlation of testicular spermatogenesis function were compared.Results FSH and LH of group A were significantly higher than those of control group,while the testosterone level was lower than that of control group （P〈0.05）.There was no significant difference in hormone levels between group B and the control group （P〉 0.05）.FSH,LH hormone levels and testieular spermatogenesis showed a negative correlation results （FSH：r=-0.572,P= 0.000;LH：r=-0.431,P-=0.000）,testosterone T and testicular spermatogenic function was positively correlated （r=0.313,P= 0.014）.PRL,E2 had no correlation with testicular spermatogenic function.Conclusion FSI4 is closely related to azoospermia and can be used as a predictor of pre-testicular puncture.h is of great significance for the treatment of azoospermia and deserves further study.

关 键 词：无精子症 血清生殖激素水平 睾丸生精功能 

分 类 号：R698.2[医药卫生—泌尿科学]