肝癌TACE治疗导致造影剂肾损害的相关危险因素分析  

Analysis of Risk Factors for Renal Damage Caused by Contrast Media in Patients With Hepatocellular Carcinoma Treated With TACE

作　　者：徐婧[1,2] 李春红[2] 王冰月[2] 向慧玲[1,2] 

机构地区：[1]天津医科大学研究生院,天津300170 [2]天津市第三中心医院肾内科/天津市肝胆疾病研究所/天津市人工细胞重点实验室/卫生部人工细胞工程技术研究中心,天津300000

出　　处：《继续医学教育》2017年第4期100-103,共4页Continuing Medical Education

摘　　要：目的对比剂肾病(CIN)是临床常见的急性医源性肾损伤,现主要分析肝癌患者造影剂肾病的发生率及相关危险因素。方法回顾性分析我院自2016年1—7月接受TACE治疗的原发性肝癌病例561例次,综合分析患者发病与主要临床指标的相关性。结果 CIN发病率16.70%,高于正常人群,数据采用SPSS 18.0分析,Logistic多元回归,提示糖尿病、基础肾功能(e GFR)、血尿酸、血浆白蛋白、总胆固醇水平是相关的危险因素,P值分别为0.012、0.001、0.007、0.026、0.020。结论糖尿病、e GFR、血尿酸、血浆白蛋白、总胆固醇水平是CIN的相危险因素。Objective Contrast-induced nephropathy （CIN） is a common clinical acute iatrogenic renal injury, this article mainly analyzes the special crowd incidence of contrast nephropathy and related risk factors. Methods Retrospective analysis from January 2016 to July 2016 with TACE treatment of primary liver cancer cases, a total of 561 cases, comprehensive analysis of pathogenesis and main clinical indicators of relevance. Results CIN incidence of 16.70%, higher than normal people, data using SPSS 18.0 analysis, Logistic multivariate regression, indicating diabetes based （eGFR）, renal function, blood uric acid, plasma albumin, total cholesterol levels are related risk factors, P values were 0.012, 0.001, 0.007, 0.026, 0.020. Conclusion Diabetes, based renal function （eGFR）, blood uric acid, plasma albumin, total cholesterol levels are related risk factors.

关 键 词：肝癌 对比剂肾病 发病率 危险因素 

分 类 号：R692[医药卫生—泌尿科学]