甲钴胺治疗糖尿病神经病变的临床分析  

Clinical Analysis of Mecobalamine in Treatment of Diabetic Neuropathy

作　　者：崔艳[1] 吴威[1] 

机构地区：[1]哈尔滨市第一医院药剂科,黑龙江哈尔滨150010

出　　处：《糖尿病新世界》2017年第1期87-88,共2页Diabetes New World Magazine

摘　　要：目的探讨甲钴胺治疗糖尿病神经病变的临床效果。方法选择2014年6月—2015年6月期间该院收治的2型糖尿病并发周围神经病变患者52例作为研究对象,随机分为对照组(26例)和观察组(26例)。观察组患者采用甲钴胺治疗,对照组患者采用维生素B_(12)治疗,比较两组患者周围神经病变治疗效果。结果治疗后,对照组NIS-LL、TSS评分显著高于观察组,组间差异有统计学意义(P<0.05)。观察组不良反应发生率与对照组比较,差异无统计学意义(P>0.05)。结论糖尿病神经病变患者采用甲钴胺治疗,临床效果可靠,且安全性较高。Objective To study the clinical effect of mecobalamine in treatment of diabetic neuropathy. Methods 52 cases of patients with type 2 diabetes and peripheral neuropathy admitted and treated in our hospital from June 2014 to June 2015 were selected as the research objects and randomly divided into two groups with 26 cases in each, the observation group were treated with mecobalamine, the control group were treated with vitamin B12, and the treatment effect of peripheral neuropathy was compared between the two groups. Results After treatment, the NIS-LL and TSS scores in the control group were obviously higher than those in the observation group, and the differences between groups had statistical significance （P〈0.05）, and the difference in the incidence rate of adverse reactions between the two groups was not obvious with- out statistical significance （P〉0.05）. Conclusion The clinical effect of mecobalamine in treatment of diabetic neuropathy is reliable, and the safety is high.

关 键 词：糖尿病神经病变 甲钴胺 维生素B12 疼痛 

分 类 号：R587[医药卫生—内分泌]