消化性溃疡合并2型糖尿病患者幽门螺旋杆菌感染与根除治疗效果分析  

Analysis of Effect of Helicobacter Pylori Infection and Eradicative Treatment for Patients with Peptic Ulcer and Type 2 Diabetes

作　　者：张春子[1] 黄震国[1] 

机构地区：[1]延吉市医院消化科,吉林延吉133000

出　　处：《糖尿病新世界》2017年第1期186-187,共2页Diabetes New World Magazine

摘　　要：目的研究消化性溃疡合并2型糖尿病患者幽门螺旋杆菌(Hp)感染情况,并对根除效果进行分析,以降低Hp感染率。方法选取2014年10月—2016年9月在该院收治住院的消化性溃疡患者80例,将其中40例消化性溃疡合并2型糖尿病患者作为观察组,40例非糖尿病消化性溃疡患者作为对照组。对比两组患者Hp感染率,并在实施相应的常规治疗后对比Hp根除率。结果观察组Hp阳性率高于对照组,两组比较差异有统计学意义(P<0.05);在实施治疗后观察组Hp根除率为62.1%,显著低于对照组的89.5%;观察组Hp根除率显著低于对照组,两组比较差异有统计学意义(P<0.05)。结论消化性溃疡合并2型糖尿病患者Hp感染率高,在治疗后Hp根治效果不佳;因此,临床上应该根据消化性溃疡合并2型糖尿病的临床特点制定有效的治疗方案,减少对患者造成的伤害。Objective To research the helicobacter pylori infection for patients with peptic ulcer and type 2 diabetes and analyze the eradicative treatment in order to reduce the Hp infection rate. Methods 80 eases of inpatients with peptic ulcer in our hospital from October 2014 to September 2016 were selected and divided into two groups with 40 cases in each, the observation group were patients with peptic ulcer and type 2 diabetes, while the control group were patients with non-dia- betes peptic ulcer, and the Hp infection rate was compared between the two groups, after the corresponding treatment, the Hp eradicativc rate was compared. Results The Hp positive rate in the observation group was higher than that in the control group, and the difference had statistical significance（P〈0.05）, and the Hp eradicative rate after treatmen（ in the observation group was obviously lower than that in the control group,（62.1% vs 89.5%）, and the difference had statistical significance, （P〈0.05）. Conclusion The Hp infection rate of patients with peptic ulcer and type 2 diabetes is high, and the Hp eradicarive effect is not good after treatment, therefore, we should make the effective treatment plan according to the clinical manifestations in clinic thus reducing the harm to patients.

关 键 词：消化性溃疡 2型糖尿病 幽门螺旋杆菌 根除效果 

分 类 号：R587.1[医药卫生—内分泌]